Huber, Philipp M.
Afzal, Naveed
Arya, Manit
Boxler, Silvan
Dudderidge, Tim
Emberton, Mark
Guillaumier, Stephanie
Hindley, Richard G.
Hosking-Jervis, Feargus
Leemann, Lucas
Lewi, Henry
McCartan, Neil
Moore, Caroline M.
Nigam, Raj
Odgen, Chris
Persad, Raj
Virdi, Jaspal
Winkler, Mathias
Ahmed, Hashim U.
Article History
Received: 3 December 2019
Accepted: 3 June 2020
First Online: 7 July 2020
Compliance with ethical standards
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: Ahmed received funding from the Medical Research Council (UK) for this study. Ahmed and Emberton received an unrestricted grant from Sonacare Inc. for this work. Ahmed’s research is supported by core funding from the United Kingdom’s National Institute of Health Research (NIHR) Imperial Biomedical Research Centre. Ahmed currently receives funding from the Wellcome Trust, Medical Research Council (UK), Prostate Cancer UK, Cancer Research UK, The BMA Foundation, The Urology Foundation, The Imperial Health Charity, Sonacare Inc., Trod Medical and Sophiris Biocorp for trials and studies in prostate cancer. Ahmed is a paid medical consultant for Sophiris Biocorp, Sonacare Inc. and BTG/Galil. Mark Emberton receives research support from the United Kingdoms’s National Institute of Health Research (NIHR) UCLH/UCL Biomedical Research Institute. He is an NIHR Senior Investigator. Emberton receives funding from NIHR-i4i, Medical Research Council (UK), Cancer Research UK, The Jon Moulton Foundation, Sonacare Inc., Trod Medical, and Sophiris Biocorp for trials in prostate cancer. Emberton is a medical consultant to Sonacare Inc., Sophiris Biocorp, Steba Biotech, Exact Imaging and Profound Medical. Moore receives funding from the National Institute for Health Research, The European Association of Urology Research Foundation, Prostate Cancer UK, Movember and the Cancer Vaccine Institute, for clinical prostate cancer research. She has received advisory board fees for Genomic Health. Ahmed, Emberton, Hindley, Moore, Boxler and Arya are all proctors for HIFU and are paid for training other surgeons in this procedure. Emberton, Freeman and Hindley have loan notes/stock options in Nuada Medical Ltd (UK). Winkler receives a travel grant and a loan of device from Zicom Biobot. None of the other authors have anything to declare.
: All cases had to be prospectively and consecutively entered into an academic registry according to UK national guidelines. Therapy options were discussed in a multidisciplinary meeting. Before treatment information on the advantages and disadvantages of the procedure had to be discussed with all patients. Written consent on therapy modality were given by all cases.