Chen, Charles D.
Joseph-Mathurin, Nelly
Sinha, Namita
Zhou, Aihong
Li, Yan
Friedrichsen, Karl
McCullough, Austin
Franklin, Erin E.
Hornbeck, Russ
Gordon, Brian
Sharma, Vijay
Cruchaga, Carlos
Goate, Alison
Karch, Celeste
McDade, Eric
Xiong, Chengjie
Bateman, Randall J.
Ghetti, Bernardino
Ringman, John M.
Chhatwal, Jasmeer
Masters, Colin L.
McLean, Catriona
Lashley, Tammaryn
Su, Yi
Koeppe, Robert
Jack, Clifford
Klunk, William E.
Morris, John C.
Perrin, Richard J.
Cairns, Nigel J.
Benzinger, Tammie L. S.
Funding for this research was provided by:
National Institutes of Health (P30AG066444, P01AG026276, P01AG03991, UF1AG032438, U19 AG032438, U19 AG024904, U19AG032438, P30NS098577, K01AG053474)
National Science Foundation (DGE-1745038)
Alzheimer's Association (AARFD-20-681815)
Article History
Received: 12 March 2021
Revised: 29 June 2021
Accepted: 1 July 2021
First Online: 28 July 2021
Declarations
:
: J.C. has served on a medical advisory board for Otsuka Pharmaceuticals. GE Healthcare holds a license agreement with the University of Pittsburgh based on the PiB-PET technology described in this manuscript. W.E.K. is a co-inventor of PiB and, as such, has a financial interest in this license agreement. GE Healthcare provided no grant support for this study and had no role in the design or interpretation of results or preparation of this manuscript. All other authors have no conflicts of interest with PiB-PET and had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. J.C.M. is funded by NIH grants # P30 AG066444; P01AG003991; P01AG026276; U19 AG032438; and U19 AG024904. Neither J.C.M. nor his family owns stock or has equity interest (outside of mutual funds or other externally directed accounts) in any pharmaceutical or biotechnology company. T.L.S.B. has investigator-initiated research funding from the NIH, the Alzheimer’s Association, the Barnes-Jewish Hospital Foundation, and Avid Radiopharmaceuticals (a wholly owned subsidiary of Eli Lilly); participates as a site investigator in clinical trials sponsored by Avid Radiopharmaceuticals, Eli Lilly, Biogen, Eisai, Jaansen, and Roche; serves as an unpaid consultant to Eisai and Siemens; and is on the Speaker’s Bureau for Biogen.
: Data are available by request to the Knight ADRC (knightadrc.wustl.edu/research/resourcerequest.htm) and the DIAN-Obs (dian.wustl.edu/our-research/observational-study/dian-observational-study-investigator-resources/data-request-terms-and-instructions/).