Wurster, Claudia D. http://orcid.org/0000-0003-0411-9968
,
Steinacker, Petra
Günther, René
Koch, Jan C.
Lingor, Paul
Uzelac, Zeljko
Witzel, Simon
Wollinsky, Kurt
Winter, Benedikt
Osmanovic, Alma
Schreiber-Katz, Olivia
Al Shweiki, Rami
Ludolph, Albert C.
Petri, Susanne
Hermann, Andreas
Otto, Markus
Funding for this research was provided by:
Bundesministerium für Bildung und Forschung (project FTLDc 01GI1007A)
PreFrontAls (01ED1512)
Amyotrophic Lateral Sclerosis Association
Fondation Thierry Latran
Charcot Foundation for ALS Research
Hermann und Lilly Schilling Stiftung
Article History
Received: 15 August 2019
Revised: 13 September 2019
Accepted: 16 September 2019
First Online: 24 September 2019
Compliance with ethical standards
:
: The authors declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: CDW has received honoraria from Biogen as an Advisory board member and for lectures and as a consultant from Hoffmann-La Roche. She also received travel expenses from Biogen. PS, SW, KW and MRAS report no disclosures. RG has received honoraria from Biogen as an Advisory board member. JCK has received financial research support form TEVA Pharmaceuticals and honoraria as speaker/consultant for AbbVie, Allergan, Biogen, Ipsen and AveXis/Novartis. PL has received financial research support from TEVA Pharmaceuticals and honoraria as speaker/consultant for AbbVie, Atheneum Partners, BIAL, Desitin, Licher MT, Medtronic, Novartis. ZU has received honoraria from Biogen as a consultant. BW has received honoraria from Biogen for a lecture. AO has received honoraria from Biogen as a consultant. OSK has received honoraria as a speaker/consultant and/or funding for travel expenses from the Deutsche Gesellschaft für Muskelkranke (DGM e.V.), Novartis, Biogen GmbH, the Jain Foundation. She received academic research support by Ludwig-Maximilians-University of Munich, FoeFoLe program, Reg.-No. 747, 11/11–05/13, and MHH Young Faculty Program, 2018–2020 as well as research support by foundations and societies by the Friedrich-Baur-GmbH, Burgkunstadt 12/13–12/15 and the Deutsche Gesellschaft für Muskelkranke (DGM e.V.), 2019–20. ACL received financial research support from AB Science, Biogen Idec, Cytokinetics, GSK, Orion Pharma, Novartis, TauRx Therapeutics Ltd. and TEVA Pharmaceuticals. He also has received honoraria as a consultant from Mitsubishi, Orion Pharma, Novartis, Teva and as an Advisory board member of Biogen and Hoffmann-La Roche. SP has received honoraria as speaker/consultant from Biogen Idec, Novartis, Cytokinetics, TEVA Pharmaceuticals, Desitin. AH has received honoraria from Biogen and Desitin as a consultant. MO received honoraria as consultant from Biogen, Axon and Fujirebio.
: The study was approved by the local ethics committees of the centers involved in Ulm, Dresden, Göttingen and Hannover (approval number at central study center at Ulm University 19/12; 2012) and all patients or their relatives (legal guardian) gave informed written consent to participate in the study.