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Article History

Received: 8 February 2020

Revised: 13 March 2020

Accepted: 14 March 2020

First Online: 28 March 2020

Compliance with ethical standards

:

: JH reports a grant for OCT research from the Friedrich-Baur-Stiftung and Merck, personal fees and non-financial support from Merck, Alexion, Novartis, Roche, Santhera, Biogen, Heidelberg Engineering, Sanofi Genzyme and non-financial support of the Guthy-Jackson Charitable Foundation, all outside the submitted work. MS is Joint Chief Editor of the Journal of Neurology, Editor in Chief of Frontiers of Neurootology and Section Editor of F1000. He has received speaker’s honoraria from Abbott, Actelion, Auris Medical, Biogen, Eisai, Grünenthal, GSK, Henning Pharma, Interacoustics, Merck, MSD, Otometrics, Pierre-Fabre, TEVA, UCB. He is a shareholder of IntraBio. He acts as a consultant for Abbott, Actelion, AurisMedical, Heel, IntraBio, and Sensorion. TBE received honoraria for lecturing from Actelion and Sanofi-Genzyme. SAS has received honoraria from Actelion Pharma. TK has received travel expenses and speaker honoraria from Bayer Vital, Teva Pharma, Merck, Novartis Pharma, Sanofi-Aventis/Genzyme, CLS Behring, Roche Pharma and Biogen as well as grant support from Bayer-Schering AG, Novartis and Chugai Pharma. AL-H has received travel expenses from BioMarin. EM has received travel reimbursement from Sobi and Dr. Schär and was paid for advisory services from Sobi and Biomarin. All other authors (MM, CS, BH, RS, and SAS) have nothing to disclose and no conflicts of interest.

: The study was performed in accordance with the Helsinki II Declaration and approved by the ethics committee of the Ludwig-Maximilians-University, Munich, Medical Faculty (part of project no 280-16).

: All participants (or their legal representatives) gave written informed consent.