Banerjee, Gargi http://orcid.org/0000-0003-0190-7782
Forsgard, Niklas
Ambler, Gareth
Keshavan, Ashvini
Paterson, Ross W.
Foiani, Martha S.
Toombs, Jamie
Heslegrave, Amanda
Thompson, Edward J.
Lunn, Michael P.
Fox, Nick C.
Zetterberg, Henrik
Schott, Jonathan M.
Werring, David J.
Funding for this research was provided by:
Rosetrees Trust
Alzheimer’s Research UK
Stroke Association
UCLH Biomedical Research Centre
National Institute for Health Research
Wolfson Foundation
Weston Brain Institute
Alzheimer's Association
Swedish Research Council
H2020 European Research Council
Swedish State Support for Clinical Research
Alzheimer's Drug Discovery Foundation
Brain Research UK
British Heart Foundatio
University College London
Article History
Received: 28 May 2021
Revised: 9 July 2021
Accepted: 12 July 2021
First Online: 22 July 2021
Declarations
:
: RWP co-leads the NfL Consortium which received industry support from Abbvie, Biogen, Bristol Myers Squibb and Roche outside of this work and has given educational meeting sponsored by GE Healthcare. HZ has served at scientific advisory boards for Denali, Roche Diagnostics, Wave, Samumed, Siemens Healthineers, Pinteon Therapeutics and CogRx, has given lectures in symposia sponsored by Fujirebio, Alzecure and Biogen, and is a co-founder of Brain Biomarker Solutions in Gothenburg AB (BBS), which is a part of the GU Ventures Incubator Program (all not related to this study). NCF has consulted for Roche; given lectures for GE and Eli Lilly; and serves on a Data Safety Monitoring Committee for Biogen (for all of which UCL received payment; all not related to this study). JMS has received research funding and PET tracer from AVID Radiopharmaceuticals (a wholly owned subsidiary of Eli Lilly); has consulted for Roche, Eli Lilly, Biogen and Merck; received royalties from Oxford University Press and Henry Stewart Talks; given education lectures sponsored by Eli Lilly, Biogen and GE; and serves on a Data Safety Monitoring Committee for Axon Neuroscience SE (not related to this study). The remaining authors have no relevant conflicts of interest to declare.
: Ethical approval for the BOCAA study was granted in October 2015 by the NHS Health Research Authority London (REC reference 15/LO/1443). Samples collected by the Specialist Cognitive Disorders Service at the National Hospital of Neurology and Neurosurgery (NHNN), University College London Hospitals (UCLH) NHS Trust, London, UK were collected as part of a study approved by the Regional Ethics Committee at UCL.
: Informed written consent was obtained for all participants.
: Not applicable; this manuscript contains no identifiable data.