Kletenik, Isaiah http://orcid.org/0000-0001-7706-967X
Cohen, Alexander L. http://orcid.org/0000-0001-6557-5866
Glanz, Bonnie I.
Ferguson, Michael A.
Tauhid, Shahamat
Li, Jing
Drew, William
Polgar-Turcsanyi, Mariann
Palotai, Miklos
Siddiqi, Shan H.
Marshall, Gad A.
Chitnis, Tanuja
Guttmann, Charles R. G.
Bakshi, Rohit
Fox, Michael D. http://orcid.org/0000-0001-8848-6399
Funding for this research was provided by:
National Institute of Mental Health (K23MH120510, R21MH126271, R56 AG069086, R01MH113929, R01MH115949)
National Institute on Aging (R56AG069086, R01AG060987)
Article History
Received: 24 March 2023
Revised: 24 July 2023
Accepted: 26 July 2023
First Online: 2 August 2023
Declarations
:
: Rohit Bakshi has received consulting fees from Bristol-Myers Squibb and EMD Serono and research support from Bristol-Myers Squibb, EMD Serono, and Novartis. The other authors report no competing interests.
: The study was approved by Mass General Brigham/Partners Institutional Review Board Protocols 2015P001248, 2020P002987 and 2020P000737 and all participants provided written informed consent. This study has been approved by the appropriate ethics committee and has been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments.
: The functional connectivity data equivalent to that used in this study is available online through the Harvard Dataverse at: ExternalRef removed and the pipeline used to prepare the functional connectivity data is available at: ExternalRef removed. The code to prepare structural connectivity maps is available at: ExternalRef removed and the structural connectivity data is available at: ExternalRef removed. Statistical analyses were performed in MatLab (version 2019b) or SPSS (version 27.0.1.0). MS lesion data is available for review upon reasonable request.