Czogalla, Bastian http://orcid.org/0000-0001-6589-4736
Kuhn, Christina
Heublein, Sabine
Schmöckel, Elisa
Mayr, Doris
Kolben, Thomas
Trillsch, Fabian
Burges, Alexander
Mahner, Sven
Jeschke, Udo
Hester, Anna
Article History
Received: 10 August 2019
Accepted: 30 August 2019
First Online: 4 September 2019
Compliance with ethical standards
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: A.H. has received research grants from the “Walter Schulz Stiftung” and honoraria from Roche and Pfizer. S.M. received research support, advisory board, honoraria and travel expenses from AstraZeneca, Clovis, Medac, MSD, PharmaMar, Roche, Sensor Kinesis, Tesaro and Teva. F.T. declares research support, advisory board, honoraria and travel expenses from AstraZeneca, Medac, PharmaMar, Roche, and Tesaro. S.H. reports grants from Baden-Württemberg Ministry of Science, Research and the Arts, from StuRa Ruprecht-Karls-University of Heidelberg, FöFoLe LMU Munich Medical Faculty, grants from FERRING, personal fees from Roche, other from Astra Zeneca, grants from Novartis Oncology, grants and non-financial support from Apceth GmbH, non-financial support from Addex and grants from Heuer Stiftung. She further reports grants from Deutsche Forschungsgemeinschaft within the funding program Open Access Publishing, by the Baden-Württemberg Ministry of Science, Research and the Arts and by Ruprecht-Karls-University Heidelberg, outside the submitted work. All other authors declare no conflicts of interest.
: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. The current study was approved by the Ethics Committee of the Ludwig-Maximilians-University, Munich, Germany (approval number 227-09 and 18-392).
: This study used tumor tissue that had initially been collected for histo-pathological diagnostics. At the time, the tissue was examined for the current study, all diagnostic procedures had already been fully completed, and the tissue used was thus classified as left-over material. All patient data were fully anonymized, the Ethics Committee of the Ludwig-Maximilians-University (Munich, Germany) approved the study (227-09 and 18-392), and the study was performed according to the standards set in the Declaration of Helsinki 1975. As per declaration of our ethics committee, no written informed consent of the participants or permission to publish is needed given the circumstances described above. Researchers were blinded from patient data during experimental and statistical analyses.