Longchamps, R. J.
Yang, S. Y. http://orcid.org/0000-0002-6327-0847
Castellani, C. A.
Shi, W.
Lane, J.
Grove, M. L.
Bartz, T. M.
Sarnowski, C.
Liu, C.
Burrows, K.
Guyatt, A. L.
Gaunt, T. R.
Kacprowski, T.
Yang, J.
De Jager, P. L.
Yu, L.
Bergman, A.
Xia, R.
Fornage, M.
Feitosa, M. F.
Wojczynski, M. K.
Kraja, A. T.
Province, M. A.
Amin, N.
Rivadeneira, F.
Tiemeier, H.
Uitterlinden, A. G.
Broer, L.
Van Meurs, J. B. J.
Van Duijn, C. M.
Raffield, L. M.
Lange, L.
Rich, S. S.
Lemaitre, R. N.
Goodarzi, M. O.
Sitlani, C. M.
Mak, A. C. Y.
Bennett, D. A.
Rodriguez, S.
Murabito, J. M.
Lunetta, K. L.
Sotoodehnia, N.
Atzmon, G.
Ye, K.
Barzilai, N.
Brody, J. A.
Psaty, B. M.
Taylor, K. D.
Rotter, J. I.
Boerwinkle, E.
Pankratz, N.
Arking, D. E.
Funding for this research was provided by:
National Heart, Lung, and Blood Institute (R01HL13573, R01HL144569)
Article History
Received: 23 September 2021
Accepted: 22 October 2021
First Online: 2 December 2021
Declarations
:
: Psaty serves on the Steering Committee of the Yale Open Data Access Project funded by Johnson & Johnson. All other authors declare no conflict of interest.
: ALSPAC: Ethical approval for the study was obtained from the ALSPAC Ethics and Law Committee and the Local Research Ethics Committees. Informed consent for the use of data collected via questionnaires and clinics was obtained from participants following the recommendations of the ALSPAC Ethics and Law Committee at the time. ARIC: Institutional Review Board approvals were obtained by the coordinating center and each ARIC study center. The research was conducted in accordance with the principles described in the Helsinki Declaration. All subjects in the ARIC study gave informed consent. CHS: CHS was approved by institutional review committees at each field center and individuals in the present analysis had available DNA and gave informed consent including consent to use of genetic information for the study of cardiovascular disease. FHS: The Boston University Medical Campus Institutional Review Board approved the FHS genome-wide genotyping. MESA: All MESA participants provided written and informed consent to participate in genetic studies. All study sites received approval to conduct this research from local Institutional Review Boards. ROS/MAP: All participants provided written informed consent and approval was obtained from an institutional review board. Participants also signed a repository consent to allow their data to be shared. SHIP: The study has been conducted according to the recommendations of the Declaration of Helsinki. The study protocol of SHIP was approved by the medical ethics committee of the University of Greifswald. Written informed consent was obtained from each of the study participants. UK Biobank: Research was approved by UK Biobank to ensure consistent with participant’s consent and framework of data access.