Funding for this research was provided by:
Instituto de Salud Carlos III (PI15/01934, PI16/02064)
Received: 26 October 2018
Accepted: 21 February 2019
First Online: 19 March 2019
Compliance with ethical standards
: The authors declare no conflict of interest.
: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
: Informed consent was obtained from all individual participants included in the study.