Funding for this research was provided by:
Agencia Estatal de Investigación (MINECO/FEDER MAT2017-85999-P)
Received: 5 June 2019
Accepted: 27 August 2019
First Online: 6 September 2019
Compliance with ethical standards
: The authors declare that they have no conflict of interest.
: The experiment was developed in accordance with the guidelines of the US National Institute of Health (NIH for Care and Use of Laboratory Animals) and European Directive 86/609/EEC regarding the care and use of animals for experimentation. The study also complied with the European Directive 2010/63/EU about the protection of animals used for scientific purposes and with all local laws and regulations. Animals were adequately housed; food and water were provided daily ad libitum with rabbit-maintenance Harlan-Teckland Lab Animal Diets (2030). The researchers obtained the approval of the Ethics Committee of the Institution (CCMI-Ref 028/16).