Received: 24 November 2018
Revised: 13 April 2019
Accepted: 8 May 2019
First Online: 24 May 2019
Compliance with ethical standards
: M. Schenk, S. Lackner and H. Mangge declare no competing interests. W. J. Schnedl received speaking honoraria from Sciotec. F. Forster is employed by Sciotec. The authors are grateful for the free supply of DAOSIN<sup>®</sup> capsules from Sciotec. Study monitoring and analysis of the data with BioTeSys GmbH was remunerated by Sciotec.
: Written informed consent was obtained, the study was monitored, and the data was analyzed anonymously by BioTeSys GmbH, Esslingen (Germany). The study was done in accordance with the Helsinki Declaration of 1975, as revised in 2000 and 2008. The Ethical Committee of the Medical University in Graz approved this study (29-474 ex 16/17).