Mosconi, Paola http://orcid.org/0000-0003-0415-3744
Guerra, Tommaso http://orcid.org/0000-0002-5248-5981
Paletta, Pasquale http://orcid.org/0000-0001-7559-0170
D’Ettorre, Antonio http://orcid.org/0000-0002-5880-4234
Ponzio, Michela http://orcid.org/0000-0001-5245-0474
Battaglia, Mario Alberto http://orcid.org/0000-0002-8106-8239
Amato, Maria Pia
Bergamaschi, Roberto http://orcid.org/0000-0002-1397-511X
Capobianco, Marco http://orcid.org/0000-0003-2501-2932
Comi, Giancarlo
Gasperini, Claudio http://orcid.org/0000-0002-3959-4067
Patti, Francesco
Pugliatti, Maura
Ulivelli, Monica http://orcid.org/0000-0003-3463-6341
Trojano, Maria http://orcid.org/0000-0002-6329-8946
Lepore, Vito http://orcid.org/0000-0002-5466-780X
Aguglia, U.
Amato, MP.
Ancona, AL.
Ardito, B.
Avolio, C.
Balgera, R.
Banfi, P.
Barcella, V.
Barone, P.
Bellantonio, P.
Berardinelli, A.
Bergamaschi, R.
Bertora, P.
Bianchi, M.
Bramanti, P.
Brescia Morra, V.
Brichetto, G.
Brioschi, AM.
Buccafusca, M.
Bucello, S.
Busillo, V.
Calchetti, B.
Cantello, R.
Capobianco, M.
Capone, F.
Capone, L.
Cargnelutti, D.
Carozzi, M.
Cartechini, E.
Cavaletti, G.
Cavalla, P.
Celani, MG.
Clerici, R.
Clerico, M.
Cocco, E.
Torri Clerici, V.
Coniglio, MG.
Conte, A.
Corea, F.
Cottone, S.
Crociani, P.
D’Andrea, F.
Danni, MC.
De Luca, G.
de Pascalis, D.
De Riz, M.
De Robertis, F.
De Rosa, G.
De Stefano, N.
Della Corte, M.
Di Sapio, A.
Docimo, R.
Falcini, M.
Falcone, N.
Fermi, S.
Ferraro, E.
Ferrò, MT.
Fortunato, M.
Foschi, M.
Gajofatto, A.
Gallo, A.
Gallo, P.
Gatto, M.
Gazzola, P.
Giordano, A.
Granella, F.
Grasso, MG.
Grimaldi, LME.
Iaffaldano, P.
Immovilli, P.
Imperiale, D.
Inglese, M.
Iodice, R.
Leva, S.
Leuzzi, V.
Lugaresi, A.
Lus, G.
Maimone, D.
Mancinelli, L.
Maniscalco, GT.
Marfia, GA.
Margari, L.
Marinelli, F.
Marini, B.
Marson, A.
Mascoli, N.
Massacesi, L.
Melani, F.
Merello, M.
Fioretti, C.
Mirabella, M.
Montepietra, S.
Nasuelli, D.
Nicolao, P.
Pasquali, L.
Passantino, F.
Patti, F.
Pecori, C.
Peresson, M.
Pesci, I.
Piantadosi, C.
Piras, ML.
Pizzorno, M.
Plewnia, K.
Pozzilli, C.
Protti, A.
Quatrale, R.
Realmuto, S.
Ribizzi, G.
Rinalduzzi, S.
Rini, A.
Romano, S.
Filippi, M.
Ronzoni, M.
Rossi, P.
Rovaris, M.
Salemi, G.
Santangelo, G.
Santangelo, M.
Leone, A.
Sarchielli, P.
Sinisi, L.
Ferraro, D.
Solaro, C.
Spitaleri, D.
Strumia, S.
Tassinari, T.
Santuccio, G.
Tortorella, C.
Totaro, R.
Tozzo, A.
Trivelli, G.
Turano, G.
Ulivelli, M.
Valentino, P.
Venturi, S.
Vianello, M.
Zaffaroni, M.
Zarbo, R.
,
Funding for this research was provided by:
FISM
Article History
Received: 20 February 2023
Accepted: 24 May 2023
First Online: 14 June 2023
Declarations
:
: PM, TG, PP, Ad'E, MP, MAB, VL declared no conflicts of interest; AMP received compensation for grants, participation in advisory board/data safety monitoring board and/or speaking activities from Biogen, Merck Serono, Roche, Novartis, Sanofi Genzyme, BMS SQUIBB, Janssen; RB received compensation for travel, grants, participation in advisory board/data safety monitoring board and/or speaking activities from Biogen, Merck Serono, Roche, Novartis, Celgene, Janssen, Sanofi Genzyme, Teva, Almirall; MC received compensation for consulting fee and/or speaking activities from Alexion, Biogen, Merck Serono, Roche, Novartis, Beckton-Dickinson; GC received compensation for consulting fee, grants, travel, participation in advisory board/data safety monitoring board and/or speaking activities from Merck Serono, Novartis, Sanofi Genzyme, Genzyme Corporation, Merck KGgA, Celgene, F. Hoffman-La Roche, Almirall, Janssen, BMS SQUIBB, BMS; CG received compensation for participation in advisory board/data safety monitoring board and/or speaking activities from Almirall, Jansen, Bayer, Biogen, Celgene, Merck, Mylan, Novartis, Roche, Sanofi and TEVA; FP received compensation for consulting fee, grants, travel, participation in advisory board/data safety monitoring board and/or speaking activities from FISM, RELOAD Onlus, Roche Biogen, Almirall, Bayer, Bristol Myers and Squibb, Merk, Novartis, Roche, Janssen, Sanofi, Alexion; MPu received compensation for consulting fee, grants, travel, participation in advisory board/data safety monitoring board and/or speaking activities from Janssen Cilag, Merck Serono, Sanofi Genzyme, Novartis, Biogen, Bristol Myers and Squibb; MU received compensation for travel, participation in advisory board/data safety monitoring board and/or speaking activities from Roche, Biogen, Sanofi Genzyme, Merck Serono; MT received compensation for grants, travel, participation in advisory board/data safety monitoring board and/or speaking activities from Biogen, Merck, Novartis, Roche, Janssen, Sanofi, Alexion, BMS.
: The study, conducted according to the World Medical Association Declaration of Helsinki, was approved by the Ethics Committee of the coordinating centre (University of Bari, reference numbers 0055587 and 0052885), and by the local ethics committees of all centres. The protocol for this analysis was discussed and approved by the Scientific Committee of the I-MS&RD Register. Each person enrolled signed written informed consent. In some centres where data were collected before the I-MS&RD Register was set up, retrospective information was included without informed consent when the patient was not traceable because of death, transfer or other reasons, in line with local laws and regulations. This analysis does not contain any individual information.
: All the authors meet the journal’s criteria for authorship and have read and approved the article.