Shah, Manish A. http://orcid.org/0000-0002-6913-9655
Kang, Yoon-Koo
Thuss-Patience, Peter C.
Ohtsu, Atsushi
Ajani, Jaffer A.
Van Cutsem, Eric
Hoersch, Silke
Harle-Yge, Marie-Laurence
de Haas, Sanne Lysbet
Funding for this research was provided by:
F. Hoffmann-La Roche
Article History
Received: 12 October 2018
Accepted: 26 December 2018
First Online: 31 January 2019
Compliance with ethical standards
:
: This exploratory biomarker analysis has not been presented previously. Selected baseline data and univariate analyses have been published in the primary analysis: Thuss-Patience et al. [CitationRef removed].
: Manish A. Shah has received research funding from Roche, Boston Biomedical, and Merck. Yoon-Koo Kang has acted in a consulting or advisory role for Novartis, Roche, BMS, Ono, Daehwa, and Blueprint and has received research funding from Daehwa. Peter C. Thuss-Patience has acted in a consulting or advisory role for Roche, Lilly, Pfizer, MSD, BMS, and Nordic and has received research funding (institutional support) from GSK and Novartis, and travel, accommodation, and expenses from Roche, Merck-KGaA, and TEVA. Atsushi Ohtsu has received research funding from BMS and a family member is employed by Celgene. Jaffer A. Ajani has received honoraria from BMS, Merck, Lilly, Taiho, and Astellas, has acted in a consulting or advisory role for Lilly, BMS, Insys, and AstraZeneca Medpace, and has received research funding from Merck, Delta-Fly, Gilead, Roche, and BMS. Eric Van Cutsem has acted in a consulting or advisory role for Bayer, Lilly, Roche, and Servier, and has received research funding (institutional support) from Amgen, Bayer, Boehringer, Lilly, Novartis, Roche, Sanofi, Celgene, Servier, Merck-KGaA, Merck, and Ipsen. Silke Hoersch is employed by KOEHLER eClinical and F. Hoffmann-La Roche. Marie-Laurence Harle-Yge is employed by F. Hoffmann-La Roche. Sanne Lysbet de Haas is employed by F. Hoffmann-La Roche.
: GATSBY was conducted in accordance with Good Clinical Practice and the Declaration of Helsinki. The protocol was approved at each site by the local ethics committee/institutional review board. All patients provided written informed consent.