Nishikawa, Kazuhiro http://orcid.org/0000-0003-1213-2732
Tsuburaya, Akira
Yoshikawa, Takaki
Takahashi, Masazumi
Tanabe, Kazuaki
Yamaguchi, Kensei
Yoshino, Shigefumi
Namikawa, Tsutomu
Aoyama, Toru
Rino, Yasushi
Kawada, Junji
Tsuji, Akihito
Taira, Koichi
Kimura, Yutaka
Kodera, Yasuhiro
Hirashima, Yoshinori
Yabusaki, Hiroshi
Hirabayashi, Naoki
Fujitani, Kazumasa
Miyashita, Yumi
Morita, Satoshi
Sakamoto, Junichi
Article History
Received: 18 November 2017
Accepted: 19 February 2018
First Online: 27 February 2018
Compliance with ethical standards
:
: The individual conflict of interest disclosure is as follows: K. Nishikawa has received honoraria from Chugai, Taiho, Yakult, Eli Lilly, Tsumura, and EA Pharma, and research funding from Yakult and Taiho, outside the submitted work. T. Yoshikawa has received lecture fees from Chugai, Taiho, Yakult, Eli Lilly and Ono, and for advisory work from Ono and MSD, outside the submitted work. K. Yamaguchi has received personal fees from Chugai, Taiho, Yakult, Takeda, Merck and Eli Lilly, and research funding from MSD, Merck, Bristol, Ono, Dainippon Sumitomo, Taiho, Daiichi-Sankyo and Yakult, outside the submitted work. S. Yoshino has received honoraria from Chugai, Taiho, Ono and Eli Lilly, outside the submitted work. Y. Kodera has received research funding from Chugai, Taiho, Daiichi-Sankyo, Bristol-Myers, Eli Lilly, Otsuka, Takeda, Yakult, CSL Behring, Pfizer, Ono, Kaken, Tsumura, EA Pharma, Novartis, KCI and the Japan Blood Products Organization, outside the submitted work. S. Morita has received honoraria from Chugai and Taiho, outside the submitted work. J. Sakamoto has received consultant fee from Takeda, and Honoraria from Tsumura and Chugai, outside the submitted work. None of the remaining authors have potential conflicts of interest to declare.
: This trial was conducted in compliance with the ethical principles of the Declaration of Helsinki and the Ethical Guidelines for Clinical Studies of the Japanese Ministry of Health, Labour and Welfare. This trial was approved by the institutional review boards or ethics committees at all participating centers. This trial was registered with ClinicalTrials.gov (NCT01412294).