Funding for this research was provided by:
Japan Agency for Medical Research and Development (16lk0201021h0004)
Article History
Received: 25 May 2016
Accepted: 11 July 2016
First Online: 15 July 2016
Compliance with ethical standards
: This is a review article, and does not contain any study involving human participants or animals by the authors.
: Kazumoto Iijima has received Grants from Japan Agency for Medical Research and Development (16lk0201021h0004), and from Japan Medical Association Center for Clinical Trials (CCT-B-2001), personal fees for Safety Review Committee and lecture from Zenyaku Kogyo Co., Ltd., and lecture and manuscript fees from Chugai Pharmaceutical Co., Ltd., during the conduct of the study. KI has also has received grants from Novartis Pharma K.K., Japan Blood Product Organization, Pfizer Japan, Inc., Kyowa Hakko Kirin Co., Ltd., AbbVie LLC, JCR Pharmaceuticals Co., Ltd., Daiichi Sankyo, Co., Ltd., Genzyme Japan K.K., Teijin Pharma Ltd., Miyarisan Pharmaceutical Co., Ltd., CSL Behring, Novo Nordisk Pharma Ltd., AIR WATER MEDICAL Inc., and Astellas Pharma Inc., Lecture fees from Pfizer Japan, Inc., Asahi Kasei Pharma Corp., Kowa Pharmaceutical Co., Ltd., MSD, ALEXION Pharmaceuticals, AstraZeneca K.K., Meiji Seika Pharma Co., Ltd., Novartis Pharma K.K., Daiichi Sankyo, Co., Ltd., Springer Japan, Medical Review Co. Ltd., Boehringer Ingelheim, and NIKKEI RADIO BROADCASTING CORPORATION, and consulting fees from Astellas Pharma Inc., ONO PHARMACEUTICAL CO., LTD. and Takeda Pharmaceutical Company Limited, outside the submitted work. Mayumi Sako has received personal fees for Safety Review Committee and lecture from Zenyaku Kogyo Co., Ltd. during the conduct of the study. Kandai Nozu has received lecture fees from Taisho Pharma and Novartis Pharma outside the submitted work.