Received: 19 February 2019
Accepted: 20 May 2019
First Online: 30 May 2019
Compliance with ethical standards
: Dr Yap reported consulting for and receiving honoraria, travel support from Novartis, Pfizer, Lilly, Astra Zeneca, Roche, Eisai, and research support from Novartis.
: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. This study was done under approval of SingHealth Centralised Institutional Review Board (Reference Number: CIRB 2004/422/B) and was conducted according to institutional and ethical rules concerning research on patients, with waiver of consent.