Moy, Beverly http://orcid.org/0000-0003-3472-1140
Oliveira, Mafalda
Saura, Cristina
Gradishar, William
Kim, Sung-Bae
Brufsky, Adam
Hurvitz, Sara A.
Ryvo, Larisa
Fagnani, Daniele
Kalmadi, Sujith
Silverman, Paula
Delaloge, Suzette
Alarcon, Jesus
Kwong, Ava
Lee, Keun Seok
Ang, Peter Cher Siang
Ow, Samuel Guan Wei
Chu, Sung-Chao
Bryce, Richard
Keyvanjah, Kiana
Bebchuk, Judith
Zhang, Bo
Oestreicher, Nina
Bose, Ron
Chan, Nancy
Funding for this research was provided by:
Puma Biotechnology Inc
Article History
Received: 23 December 2020
Accepted: 27 March 2021
First Online: 28 April 2021
Declarations
:
: Beverly Moy: Consulting or Advisory Role: Motus. Research Funding: Puma Biotechnology (Inst). Mafalda Oliveira: Honoraria: Roche, Novartis, Seattle Genetics. Consulting or Advisory Role: Roche/Genentech, GlaxoSmithKline, Puma Biotechnology, AstraZeneca, Seattle Genetics. Research Funding: Philips Healthcare (Inst), Roche/Genentech (Inst), Novartis (Inst), AstraZeneca (Inst), Immunomedics (Inst), Seattle Genetics (Inst), Boehringer Ingelheim (Inst), GlaxoSmithKline (Inst), Cascadian Therapeutics (Inst), Sanofi (Inst), Celldex Therapeutics (Inst), Bayer (Inst), PIQUR Therapeutics (Inst), Puma Biotechnology (Inst), Zenith Epigenetics (Inst). Travel, Accommodations, Expenses: Roche, Novartis, Grünenthal Group, Pierre Fabre, GP Pharm, Eisai. Cristina Saura. Consulting or Advisory Role: AstraZeneca, Celgene, Daiichi Sankyo, Eisai, F. Hoffmann-La Roche Ltd, Genomic Health, Merck, Sharp and Dohme España S.A., Novartis, Odonate Therapeutics, Pfizer, Philips Healthwork, Pierre Fabre, prIME Oncology, Puma, Synthon and Sanofi Aventis. Research Funding: Genentech (Inst), AstraZeneca (Inst), Roche (Inst), Macrogenics (Inst), Novartis (Inst), Pfizer (Inst), Puma Biotechnology (Inst), Synthon (Inst), PIQUR Therapeutics (Inst) Daiichi Sankyo (Inst), Eli Lilly and Company (Inst), Genentech (Inst), Immunomedics (Inst), Merck, Sharp and Dohme España S.A. (Inst), and Zenith Pharma (Inst). Travel, Accommodations, Expenses: Pfizer, Novartis, Roche, AstraZeneca, Genomic Health, Puma Biotechnology. William Gradishar: Consulting or Advisory Role: Genentech/Roche, AstraZeneca, Pfizer, Puma. Sung-Bae Kim: Honoraria: DAEHWA Pharmaceutical, ISU Abxis. Consulting or Advisory Role: Eli Lilly (Inst), AstraZeneca, DAEHWA Pharmaceutical, ISU Abxis. Research Funding: Novartis (Inst), Dongkook Pharma (Inst), Sanofi-Genzyme (Inst). Adam Brufsky: Consulting or Advisory Role: Pfizer, Genentech/Roche, Agendia, Celgene, Novartis, Bayer, Eli Lilly, Biotheranostics, NanoString Technologies, Genomic Health, Puma Biotechnology, Bioarray Therapeutics, Merck, Myriad Pharmaceuticals, Eisai, Immunomedics, Seattle Genetics, Daiichi Sankyo/Eli Lilly. Sara A. Hurvitz: Research Funding: Ambrx, Amgen, AstraZeneca, Arvinas, Bayer, Daiichi Sankyo, Genentech/Roche, GSK, Immunomedics, Lilly, Macrogenics, Novartis, Pfizer, OBI Pharma, Pieris, PUMA, Radius, Sanofi, Seattle Genetics, Dignitana, Zymeworks, Phoenix Molecular Designs, Ltd. Travel: Lilly. Larisa Ryvo: No relationships to disclose. Daniele Fagnani: No relationships to disclose. Sujith Kalmadi: Stock and Other Ownership Interests: Immunomedics, AstraZeneca. Consulting or Advisory Role: Bayer, AbbVie/Genentech, AstraZeneca/MedImmune, EMD Serono, Lilly. Speakers’ Bureau: Genentech/Roche, Pharmacyclics/Janssen, AstraZeneca/MedImmune, Takeda, Bayer, Novartis/Pfizer. Research funding: Genentech/Roche, Tesaro, Pfizer, EMD Serono, Novocure, AbbVie/Genentech. Paula Silverman: No relationships to disclose. Suzette Delaloge: Consulting or Advisory Role: AstraZeneca. Research Funding: AstraZeneca (Inst), Pfizer (Inst), Roche/Genentech (Inst), Puma (Inst), Eli Lilly (Inst), Novartis (Inst), Sanofi (Inst). Travel, Accommodations, Expenses: Pfizer, AstraZeneca, Roche. Jesus Alarcon: No relationships to disclose. Ava Kwong: No relationships to disclose. Keun Seok Lee: Consulting or Advisory Role: Eli Lilly, AstraZeneca, Novartis, Roche. Research Funding: Dong-A ST (Inst). Peter Cher Siang Ang: No relationships to disclose. Samuel Guan Wei Ow: Consulting or Advisory Role: AstraZeneca, Eli Lilly, Novartis, Pfizer. Sung-Chao Chu: No relationships to disclose. Richard Bryce: Employment: Puma Biotechnology. Leadership: Puma Biotechnology. Stock and Other Ownership Interests: Puma Biotechnology. Travel, Accommodations, Expenses: Puma Biotechnology. Kiana Keyvanjah: Employment: Puma Biotechnology. Stock and Other Ownership Interests: Puma Biotechnology. Travel, Accommodations, Expenses: Puma Biotechnology. Judith Bebchuk: Employment: Puma Biotechnology. Stock and Other Ownership Interests: Puma Biotechnology. Bo Zhang: Employment: Puma Biotechnology. Stock and Other Ownership Interests: Puma Biotechnology. Nina Oestreicher: Employment: Puma Biotechnology. Stock and Other Ownership Interests: Puma Biotechnology. Ron Bose: Research funding: Puma Biotechnology (Inst). Consulting or advisory role: Genentech. Nancy Chan: No relationships to disclose.
: The protocol was approved by national/institutional ethics committees at participating sites and conducted in accordance with the Declaration of Helsinki.
: All patients provided written informed consent prior to any protocol-specific procedures or study drug administration.