Lopes Cardozo, J. M. N. http://orcid.org/0000-0003-0520-0282
Schmidt, M. K. http://orcid.org/0000-0002-2228-429X
van ’t Veer, L. J. http://orcid.org/0000-0002-9838-8298
Cardoso, F. http://orcid.org/0000-0002-6692-2249
Poncet, C. http://orcid.org/0000-0002-8635-9350
Rutgers, E. J. T. http://orcid.org/0000-0002-4244-0106
Drukker, C. A. http://orcid.org/0000-0003-3477-5499
Funding for this research was provided by:
European Organisation for Research and Treatment of Cancer (Research Grant from EORTC Breast Cancer Group and NKI)
Netherlands Cancer Insitute (Research Grant from EORTC Breast Cancer Group and NKI)
Article History
Received: 25 May 2021
Accepted: 23 June 2021
First Online: 30 June 2021
Declarations
:
: L.J. van ‘t Veer reports being shareholder in and part-time employed by Agendia NV, the commercial company that markets the 70-gene signature as MammaPrint. F. Cardoso has received personal fees from Amgen, Astellas/Medivation, AstraZeneca, Celgene, Daiichi-Sankyo, Eisai, GE Oncology, Genentech, GlaxoSmithKline, Macrogenics, Medscape, Merck-Sharp, Merus BV, Mylan, Mundipharma, Novartis, Pfizer, Pierre-Fabre, prIME Oncology, Roche, Samsung Bioepis, Sanofi, Seagen, and Teva outside the submitted work.
: This study was performed in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. The MINDACT study was approved by the ethics commitees of all participating sites. This project was approved by the MINDACT Executive Committee and MINDACT Steering Committee, after review by experts from the MINDACT Independent Review Committee, the MINDACT Statistician, and the MINDACT Ethical-Legal committee. This project was reviewed by the ethics committee who concluded it was a non-CT directive study that did not require further ethical approval, and could be performed under the scope of the MINDACT protocol and informed consent.
: All patients included in the MINDACT trial provided written informed consent. This consent allowed linkage to the Dutch national screening database.
: All authors reviewed draft and final versions of the manuscript before submission and approved the final version. The first and last authors had full access to all of the data and had final responsibility for the decision to submit for publication.