Bardia, Aditya http://orcid.org/0000-0003-4885-1157
Mayer, Ingrid
Winer, Eric
Linden, Hannah M.
Ma, Cynthia X.
Parker, Barbara A.
Bellet, Meritxell
Arteaga, Carlos L.
Cheeti, Sravanthi
Gates, Mary
Chang, Ching-Wei
Fredrickson, Jill
Spoerke, Jill M.
Moore, Heather M.
Giltnane, Jennifer
Friedman, Lori S.
Chow Maneval, Edna
Chan, Iris
Jhaveri, Komal
Funding for this research was provided by:
Genentech
Memorial Sloan-Kettering Cancer Center (P30 CA008748)
Article History
Received: 16 August 2022
Accepted: 30 October 2022
First Online: 19 November 2022
Declarations
:
: A.B. held consulting/advisory board positions at Pfizer, Novartis, Genentech, Merck, Radius Health, Immunomedics/Gilead, Sanofi, Daiichi Pharma/AstraZeneca, Phillips, Eli Lilly, Foundation Medicine, and received contracted research/grant to institution from Genentech, Novartis, Pfizer, Merck, Sanofi, Radius Health, Immunomedics/Gilead, Daiichi Pharma/AstraZeneca, and Eli Lilly. I.M. received consulting fees/ research support from Genentech and is an employee of AstraZeneca. E.W. and H.M.L. received consulting fees and research support from Genentech. C.X.M. held consulting/advisory board positions at Gilead, AstraZeneca, Sanofi-Genzyme, Jacobio, Natera, Novartis, Inivata, Biovica, Athenex, Bayer, Esai, and OncoSignal and received funding from Pfizer and Puma. B.A.P. received contracted research support to the institution from Pfizer, Novartis, Glaxo Smith Kline, Genentech/Roche, and Oncternal Therapeutics Inc., consulting fees from Dare Bioscience, Bioatla Inc. (spouse), EMD Serona (spouse), and Samumed LLC (spouse), and has stock ownership in Merck. M.B. held advisory board positions at Pfizer, Novartis, and Lilly and received speakers bureau fees from Pfizer, Novartis, and Lilly and travel expenses from Pfizer and Roche. C.L.A. held advisory board positions at Novartis, Lilly, Merck, TAIHO Oncology, Immunomedics, Daiichi Sankyo, AstraZeneca, Sanofi, OrigiMed, and Susan G. Komen Foundation, received research grant support from Pfizer, Lilly, and Takeda, and has stock ownership in Provista. S.C., M.G., C.-W.C., J.F., H.M.M., J.G., and I.C. are employees and stockholders of Roche/Genentech. J.M.S. and L.S.F. are former employees and stockholders of Roche/Genentech. E.C.M. is a former employee of Seragon. K.J. received consulting fees from AbbVie, AstraZeneca, Blueprint Medicines, Biotheranostics, BMS, Genentech, Jounce Therapeutics, Lilly Pharmaceuticals, Novartis, Pfizer, Seattle Genetics, SunPharma Pvt Ltd, and Taiho Oncology and contracted research grants to institution from ADC Therapeutics, AstraZeneca, Clovis Oncology, Debio Pharmaceuticals, Genentech, Immunomedics, Novartis, Lilly Pharmaceuticals, Merck/VelosBio, Novartis, Novita Pharmaceuticals, Pfizer, Puma Biotechnology, and Zymeworks.
: The appropriate research ethics committee at each clinic where patients were enrolled approved the study: (1) Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10021. (2) Massachusetts General Hospital, 55 Fruit St., Boston, MA 02114. (3) Dana Farber Cancer Institute, 450 Brookline Ave., Boston, MA 02215. (4) Seattle Cancer Care Alliance, 825 Eastlake Ave., Seattle, WA 98109. (5) Washington University, 660 S. Euclid Ave., St. Louis, MO 63110. (6) UCSD Medical Center, 3855 Health Sciences Dr., La Jolla, CA 92093. (7) Vanderbilt University Medical Center, 2220 Pierce Ave., Nashville, TN, 37232. (8) Hospital Universitari Vall d’Hebron, Passeig de la Vall d’Hebron, 119–129, 08035, Barcelona, Spain. (9) Severance Hospital, Yonsei University Health System, 50 Yonsei-ro, Seodaemun-Gu, 120–752, Seoul, South Korea. (10) Centro Integral Oncologico Clara Campal (CIOCC), Calle Oña N°10, 28050, Madrid, Spain. (11) Mount Sinai Medical Center, 1176 Fifth Ave., New York, NY 10029. (12) Vu Medisch Centrum, Dept. Medical Oncology, De Boelelaan 1117, 1081 HV, Amsterdam, the Netherlands. (13) Seoul National University Cancer Hospital, 101 Daehak-ro, Jogno-gu 110–744, Seoul, South Korea. (14) Hospital Clinico Universitario de Valencia, Avda Basco Ibanez 17, 46010, Valencia, Spain.
: Written informed consent was obtained from all individual participants included in the study.