Funding for this research was provided by:
LKC Technologies, Inc.
Received: 18 April 2016
Accepted: 11 January 2017
First Online: 3 February 2017
Compliance with ethical standards
: These conflicts of interest are relevant to this research: employment (Q. Davis and O. Kraszewska), stock ownership (Q. Davis), and study sponsorship by LKC Technologies, Inc. C. Manning has no conflict of interest.
: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. Informed consent was obtained from each subject after explanation of the nature and possible consequences of the study. The study was approved by an institutional review board (SAIRB-15-0017) and is registered at ClinicalTrials.gov (NCT02466607).