Noel, Marcus
O’Reilly, Eileen M.
Wolpin, Brian M.
Ryan, David P.
Bullock, Andrea J.
Britten, Carolyn D.
Linehan, David C.
Belt, Brian A.
Gamelin, Eric C.
Ganguly, Bishu
Yin, Donghua
Joh, Tenshang
Jacobs, Ira A.
Taylor, Carrie T.
Lowery, Maeve A.
Funding for this research was provided by:
Pfizer
Article History
Received: 1 May 2019
Accepted: 1 July 2019
First Online: 12 July 2019
Compliance with ethical standards
:
: MN is a consultant of Celgene and Taiho Oncology. CDB has received research funding to her institution from Pfizer, Eli Lilly, Celgene, EMD Serono, Five Prime, Regeneron, Tesaro, and Halozyme, and travel paid for by Five Prime, Genentech, and Amgen. EOR has received research funding to her institution from Pfizer, Celgene, Mabvax, Actabiologica, and Halozyme, and is a consultant and member of advisory panels for Celgene, Targovax, and Roche. BMW has received research funding from Celgene, and is a consultant of G1 Therapeutics, BioLineRx, and GRAIL. DR is an advisor of MPM Capital. DR is an advisor and stockholder of MPM Capital, an advisor for Oncorus and Gritsone Oncology, received royalties from Johns Hopkins University Press, Uptodate, and McGraw Hill and funding from Pfizer. DCL has received research funding to his institution from Pfizer. AJB is an advisor for Bayer, Halozyme, Taiho, and Exelixis. ML is a consultant and member of advisory boards for Celgene and Agios pharmaceuticals. ECG, DY, TH, IAJ, and CTT are employees of and hold shares in Pfizer. BG holds shares in Pfizer and is an employee of, and holds stock options in Lyell Immunopharma.
: All procedures performed in studies involving human participants were in accordance with the ethical standards of the local institutional review and privacy board and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. The study was conducted at seven centers in the United States and was also in compliance with all International Council for Harmonisation Good Clinical Practice Guidelines and all local regulatory requirements. The study is registered at ExternalRef removed, identifier NCT02732938.
: Informed consent was obtained from all individual participants included in the study.