Wick, Antje
Desjardins, Annick
Suarez, Cristina
Forsyth, Peter
Gueorguieva, Ivelina
Burkholder, Tiana
Cleverly, Ann Louise
Estrem, Shawn T.
Wang, Shuaicheng
Lahn, Michael M.
Guba, Susan C.
Capper, David
Rodon, Jordi
Funding for this research was provided by:
Eli Lilly and Company (not applicable)
Article History
Received: 4 December 2019
Accepted: 7 February 2020
First Online: 5 March 2020
Compliance with ethical standards
:
: <b>AD</b> serves on Advisory Board for Orbus Therapeutics, and Celgene, holds stock options from ISTARI Oncology, and letters of patent for Oncolytic Poliovirus for human tumors. AD’s institution receives research funding from Genentech/Roche, Celldex, Triphase Accelerator Corp., Eli Lilly and Company, Symphogen A/S, Pfizer, and Orbus Therapeutics. CS serves on Advisory Board for Pfizer, IPSEN, BMS, Astellas, Sanofi, Bayer, and MSD; is a speaker for BMS, Pfizer, IPSEN, and Astellas; received travel reimbursement from BMS, Pfizer, and Roche; reports receiving research/clinical funding from Roche. <b>PF</b> is consultant for AbbVie Inc., Ziopharm, Tocagen Inc., BMS and L.E.K. <b>JR</b> reports non-financial support and reasonable reimbursement for travel from European Journal of Cancer, Vall d’Hebron Institut of Oncology, Chinese University of Hong Kong, SOLTI, Elsevier, GLAXOSMITHKLINE; receiving consulting and travel fees from Novartis, Eli Lilly and Company, Orion Pharmaceuticals, Servier Pharmaceuticals, Peptomyc, Merck Sharp & Dohme, Kelun Pharmaceutical/Klus Pharma, Spectrum Pharmaceuticals Inc., Pfizer, Roche Pharmaceuticals, Ellipses Pharma (including serving on the scientific advisory board from 2015-present), receiving research funding from Bayer and Novartis, and serving as investigator in clinical trials with Spectrum Pharmaceuticals, Tocagen, Symphogen, BioAtla, Pfizer, GenMab, CytomX, KELUN-BIOTECH, Takeda-Millenium, GLAXOSMITHKLINE, IPSEN and travel fees from ESMO, US Department of Defense, Louisiana State University, Hunstman Cancer Institute, Cancer Core Europe, Karolinska Cancer Institute and King Abdullah International Medical Research Center (KAIMRC). <b>SE</b>, <b>IG</b>, and <b>TB</b> are employees of Eli Lilly and Company and may hold company stocks. <b>ML, SG,</b> and <b>ALC</b> are former employees of Eli Lilly and Company and hold company stocks. The other authors report no conflicts of interest.
: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards. The study was registered at ExternalRef removed as NCT01220271.
: Informed consent was obtained from all individual participants included in the study.