Olmedo, María Eugenia
Forster, Martin
Moreno, Victor
López-Criado, María Pilar
Braña, Irene
Flynn, Michael
Doger, Bernard
de Miguel, María
López-Vilariño, José Antonio
Núñez, Rafael
Kahatt, Carmen
Cullell-Young, Martin
Zeaiter, Ali
Calvo, Emiliano http://orcid.org/0000-0003-4921-829X
Article History
Received: 15 October 2020
Accepted: 22 October 2020
First Online: 11 March 2021
Declarations
:
: Martin Forster has conducted consulting and advisory services, speaking or writing engagements, or public presentations for Achilles, AstraZeneca, Bayer, BMS, Celgene, Guardant Health, Merck, MSD, Nanobiotix, Novartis, Oxford VaMedix, Pfizer, Pfizer, Roche and Takeda; his institution has received research funding from AstraZeneca, Boehringer Ingelheim, MSD and Merck; in addition, Martin Foster is supported by the UCL/UCLH NIHR Biomedical Research Centre and runs early phase studies in the NIHR UCLH Clinical Research Facility supported by the UCL ECMC. Emiliano Calvo has had a company leadership role, employment relationship or ownership interest for START Madrid, Oncoart Associated, International Cancer Consultants and HM Hospitals Group; has conducted consulting and advisory services, speaking or writing engagements, or public presentations for Astellas Pharma, Novartis, Nanobiotix, Pfizer, Janssen, GLG, Merck, Medscape, BMS, Pierre-Fabre, Gilead, Cerulean, Gehrman Consulting, Boehringen-Ingelheim, Seattle Genetics, Guidepoint, AstraZeneca, Roche/Genetech, PsiOxus, Abbvie, Celgene, Servier and Amcure; has been study international principal investigator for AstraZeneca and member of study steering committees for Novartis and BeiGene, and his institution has received financial support from Abbvie, Amgen, AstraZeneca, Bayer, Boehringer Ingelheim, Bristol-Myers Squibb, Eisai, Janssen Oncology, Hospira, Lilly, Merck, Merus, Millennium, Nanobiotix, Nektar. Novartis, OncoMed, Pfizer, PharmaMar, PsiOxus Therapeutics, Puma Biotechnology, Regeneron, Roche-Genentech, Sanofi, Spectrum Pharmaceuticals, ACEA Bio, Amcure, Cytomx, H3-Biomedicine, Incyte, Kura, LOXO, Macrogenics, Menarini, Principia, Tahio, Tesaro, BeiGene, Transgene, Takeda, Innovio, MSD, Seattle Genetics, Mersana, GSK, Daiichi, Astellas, ORCA, Boston Therapeutics, Dynavax, DebioPharma, Synthon and Rigontec. José Antonio López-Vilariño, Rafael Núñez, Carmen Kahatt and Ali Zeaiter are employees and stock owners of Pharma Mar, S.A. Martin Cullell-Young is an employee of Pharma Mar, S.A. All remaining authors have declared no conflicts of interest.
: The study was approved by the Research Ethics Committees of participating centers in Spain and the U.K. The study was conducted in full accordance with the principles of the World Medical Association Declaration of Helsinki, the International Conference of Harmonisation, and all applicable local guidelines and regulations on good clinical practice.
: All patients provided written informed consent to participate in this study.
: All patients provided written informed consent about participation in this study and the use of collated data. No individual patient data are included in this article that could be used to identify any individual.
: Not applicable.