Funding for this research was provided by:
National Institutes of Health (T32HL098054, R01CA159932, F31HL127947)
Received: 27 March 2017
Accepted: 14 June 2017
First Online: 21 June 2017
Compliance with ethical standards
: George L. Anesi, Scott D. Halpern, Michael O. Harhay, Kevin G. Volpp, and Kathryn Saulsgiver declare that they have no conflicts of interest.
: All procedures involving human participants were in accordance with the ethical standards of the Institutional Review Board at the University of Pennsylvania (IRB Protocol #814761) and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards, and registered with Clinicaltrials.gov (Protocol #NCT01526265). Informed consent was obtained from all individual participants included in the study.