Text and Data Mining valid from 2019-12-09
Received: 16 September 2019
Accepted: 30 November 2019
First Online: 9 December 2019
Compliance with ethical standards
: The authors declared no conflict of interest.
: Animals care during the experiments were carried out in keeping with agreement of the Medical Ethical Committee, National Research Centre, Egypt (Approval No. 16089) and Ethics Committee of Faculty of Pharmacy, Cairo University, Cairo, Egypt (BC 1839). Basic housing requirements and regular inspection of facilities that mandate the control of pain and suffering during the experiment were conducted. Euthanasia was done rapidly and painlessly to be sure that the animals do not suffer at any stage of the experiment. Getting-rid of the animals after termination was done rapidly by the aid of the Safety and Health Committee at National Research Centre, Dokki, Giza, Egypt.