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Article History

Received: 18 December 2018

Accepted: 28 March 2019

First Online: 16 April 2019

Compliance with ethical standards

:

: All the research protocol, procedures, euthanasia as well as ethical clearance were approved by the Board of Advanced Studies and Research, Hamdard University, Karachi. The animals used in the study were handled as per specifications described in Helsinki Resolution 1964. The acute oral toxicity test was conducted according to Organization for Economic Co-operation and Development (OECD) guideline 423 on Swiss-albino rats of (200–250 g) (Class, 2001).

: Declared none.

: In the present study, all research protocols, animal screening and euthanasia procedures are approved by the Ethical Review Board (ERB), Hamdard University. This study protocol was also approved by BASR (Board of Advanced Studies & Research), Hamdard University.