Wu, You
Al-Janabi, Hareth
Mallett, Andrew
Quinlan, Catherine
Scheffer, Ingrid E.
Howell, Katherine B.
Christodoulou, John
Leventer, Richard J.
Lockhart, Paul J.
Stark, Zornitza
Boughtwood, Tiffany
Goranitis, Ilias
Funding for this research was provided by:
National Health and Medical Research Council (GNT1113531)
Article History
Accepted: 31 March 2020
First Online: 7 April 2020
Compliance with ethical standards
:
: I. Scheffer serves on the editorial boards of Neurology® and Epileptic Disorders; may accrue future revenue on a pending patent regarding Therapeutic compound; has received speaker honoraria from Athena Diagnostics, BioMarin, UCB, GSK, Eisai, and Transgenomics; has received scientific advisory board honoraria from BioMarin, Nutricia and GSK; has received funding for travel from Athena Diagnostics, BioMarin, UCB, and GSK; and receives/has received research support from the NHMRC, ARC, NIH, Health Research Council of New Zealand, March of Dimes, the Weizmann Institute, CURE, US Department of Defense, and the Perpetual Charitable Trustees. K. Howell is supported by an Early Career Fellowship and New Investigator Project Grant from the National Health and Medical Research Council of Australia. P. Lockhart is supported by the Vincent Chiodo Foundation and receives research support from the National Health and Medical Research Council of Australia and the Orphan Disease Centre, University of Pennsylvania. YW, IG, HA, AM, CQ, JC, RJL, ZS and TB declare that they have no conflict of interest.
: Ethics approvals were granted by the Melbourne Health Human Research Ethic Committee (HREC) (Ref no.: HREC/16/MH/251), the UnitingCare Health HREC (Ref no.: 1717), the Tasmanian Health and Medical HREC (Ref no.: H0016443), and the Northern Territory Department of Health and Menzies School of Health Research HREC (Ref no.: 2017–2999), as part of the project “Australian Genomic Health Alliance: Preparing Australian for Genomic Medicine”.
: Informed consent for participation in the clinical “flagship” projects, research and publication was obtained from the parents of the enrolled children.