Shimizu, Yu http://orcid.org/0000-0002-5439-7678
Nakamura, Kiminori http://orcid.org/0000-0002-2138-1733
Kikuchi, Mani http://orcid.org/0000-0003-1144-4873
Ukawa, Shigekazu http://orcid.org/0000-0003-4084-1720
Nakamura, Koshi http://orcid.org/0000-0001-8141-7614
Okada, Emiko http://orcid.org/0000-0002-9345-0937
Imae, Akihiro
Nakagawa, Takafumi
Yamamura, Ryodai http://orcid.org/0000-0002-9342-7702
Tamakoshi, Akiko http://orcid.org/0000-0002-9761-3879
Ayabe, Tokiyoshi http://orcid.org/0000-0002-8631-5593
Funding for this research was provided by:
Japan Society for the Promotion of Science (17K11661, 18H02788, 26670322)
Center of Innovation Program (JPMJCE 1301, JPMJCE 1301, JPMJCE 1301)
Ministry of Agriculture, Forestry and Fisheries (14538261)
the Japan Foundation for Aging and Health (2015-58-2)
Mitsubishi Foundation (10492)
Article History
Received: 29 April 2021
Accepted: 1 June 2021
First Online: 8 June 2021
Declarations
:
: This study was approved by the Ethical Committee of the Faculty of Medicine (15–002, 15–045), Hokkaido University. Written informed consent was obtained from all participants. All animal experiments in this study were conducted after obtaining approval from the Institutional Animal Care and Use Committee of the National University Corporation at Hokkaido University in accordance with Hokkaido University Regulations on Animal Experimentation.
: The authors obtained written informed consent from all participants in this study.
: Not applicable.
: The authors declare no competing interests.