Kirienko, Margarita http://orcid.org/0000-0002-3923-1151
Ninatti, Gaia http://orcid.org/0000-0001-8207-1256
Cozzi, Luca http://orcid.org/0000-0001-7862-898X
Voulaz, Emanuele
Gennaro, Nicolò http://orcid.org/0000-0001-7259-6980
Barajon, Isabella
Ricci, Francesca
Carlo-Stella, Carmelo http://orcid.org/0000-0003-3144-0124
Zucali, Paolo
Sollini, Martina http://orcid.org/0000-0003-2214-6492
Balzarini, Luca
Chiti, Arturo http://orcid.org/0000-0002-5806-1856
Article History
Received: 11 December 2019
Accepted: 30 March 2020
First Online: 18 April 2020
Compliance with ethical standards
:
: The authors of this manuscript declare relationships with the following companies: Kirienko, Ninatti, Voulaz, Gennaro, Barajon, Ricci, Sollini, Balzarini—none. Cozzi—acts as Scientific Advisor to Varian Medical Systems outside the scope of the submitted work. Carlo Stella—received speaker honoraria from MSD, BMS, Amgen, Janssen, AstraZeneca; acted as scientific advisor for Genenta Science, ADC Therapeutics, Sanofi, Boehringer Ingelheim; benefited from an unrestricted Grant from Rhizen Pharmaceuticals. These honoraria and Grants are outside the scope of the submitted work. Zucali—received speaker honoraria from Astellas, Pfizer, Sanofi, Janssen, BMS, Ipsen, and Novartis; acted as scientific advisor for Astellas, Pfizer, BMS, Janssen, MSD and Novartis. All honoraria and Grants are outside the scope of the submitted work. Chiti—received speaker honoraria from General Electric and Blue Earth Diagnostics, acted as scientific advisor for Blue Earth Diagnostics and Advanced Accelerator Applications, and benefited from an unconditional Grant from Sanofi to Humanitas University. All honoraria and Grants are outside the scope of the submitted work. As above mentioned, all declared honoraria and Grants are outside the scope of the submitted work.
: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee (Humanitas Clinical and Research Center Review Board approval was obtained, authorization number 3/18, April 17, 2018) and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.
: Written informed consent was waived by the institutional review board.