Vats, Kanchan
Sarmah, Deepaneeta
Datta, Aishika
Saraf, Jackson
Kaur, Harpreet
Pravalika, Kanta
Wanve, Madhuri
Kalia, Kiran
Borah, Anupom
Dave, Kunjan R
Yavagal, Dileep R
Bhattacharya, Pallab http://orcid.org/0000-0003-2867-1650
Article History
Received: 25 September 2019
Accepted: 29 November 2019
First Online: 9 December 2019
Change Date: 1 January 2021
Change Type: Correction
Change Details: It has come to our notice that there was an inadvertent misupload of Fig. 2 (c, d) in the loading control (GAPDH) for ASIC1a and NLRP1 blots. We would like to replace the same with the correct image. This change anyhow does not affect the conclusion of the study. However, the use of GAPDH as a loading control for stroke studies sometimes is debatable (Zhai et al. 2014; Kang et al. 2018). Hence, we repeated our experiments to check the expression of ASIC1a and NLRP1 at different time points following stroke, using beta actin as a loading control. We found that at 24 h post stroke, maximal and significant expression of both ASIC1a and NLRP1 was observed (Fig. 2 e, f). The expression at 48 and 72 h post stroke were not significantly different as compared to that of sham. The expression results obtained using beta actin as a loading control were concurrent with the previous results published with GAPDH as a loading control.
Compliance with Ethical Standards
: Animal experimentation was performed as per the stated guidelines in Guide for the Care and Use of Laboratory Animals published by the Committee for the Purpose of Control and Supervision of Experiments on Animals (CPCSEA). The Institutional Animal Ethical Committee of NIPER-Ahmedabad approved the experimental protocol (NIPERA/IAEC/2017/005).
: The authors declare that they have no conflicts of interest.