Article History
Received: 3 December 2021
Accepted: 10 July 2022
First Online: 9 September 2022
Declarations
:
: There is No conflict of interest pertaining to this study.
: All procedures performed in the study involving human subjects were in accordance with the ethical standards of the institutional and national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
: Informed consent was obtained from all participants included in the study. They were informed and explained in their language about the disease in detail. Its progression and cause. The future course of disease. All the patients were explained in detail about the effect and side-effects of Amphotericin-B, Posaconazole, its dosing and cost. They were explained in detail about the surgery including the resection, its morbidity, rare chance of mortality, intra-operative frozen and given an option of opting to undergo reconstruction using autologous tissue in the form of flap in the same sitting (to which all of them approved). They were informed about the donor site morbidity and chances of flap failure. They were explained and given option of using a prosthesis verses flap, explaining the merits and demerits of each. They were also informed about the post-operative care and treatment. The probability of disease recurrence and its poor overall survival with residual morbidity was also explained. They were explained about the outcome in case they do not wish to undergo the treatment. ICU and ventilator consent was taken for each patient. Death on table consent was taken for each patient. Only after the patient and his relatives fully understood the details and gave consent for the surgery, they underwent complete multi-speciality check-up. Pre- Anaesthetic approval. Following which surgery was performed.
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