Kong, Fan-En
Tang, Yun-Qiang
Gong, Yuan-Feng
Mo, Jia-Qiang
Zhao, Yue
Li, Mei-Mei
Cheng, Wei
Li, Hao-Long
Zhu, Wen-Jie
Liu, Shan-Shan
Huang, Li
Guan, Xin-Yuan
Ma, Ning-Fang
Liu, Ming http://orcid.org/0000-0003-3222-8715
Funding for this research was provided by:
National Natural Science Foundation of China (81702400)
Guangdong Province Higher Vocational Colleges and Schools Pearl River Scholar Funded Scheme (2018)
Article History
Received: 5 November 2019
Accepted: 21 March 2020
First Online: 17 April 2020
Compliance with ethical standards
:
: The authors declare no conflicts of interest in this work.
: The study was approved by the Research Ethics Committees of Affiliated Cancer Hospital & Institute of Guangzhou Medical University. The experiments regarding the establishment of human embryonic stem cells and induced in vitro differentiation were approved and guided by the ethical committee of CITIC-Xiangya Reproductive & Genetic Hospital. The blastocysts, which were donated for the study after obtaining written informed consents from the patients undergoing assisted reproductive technology treatment, came from various clinical useless embryos, including poor quality embryos, abnormal embryos after pre-implantation genetic diagnosis (PGD), zygotes with the abnormal pronuclear number and partheno-activated embryos [CitationRef removed].
: Informed consent was obtained from all patients for being included in the study.