Received: 8 May 2020
Revised: 1 June 2020
Accepted: 4 June 2020
First Online: 25 June 2020
Compliance with ethical standards
: Massimo Breccia: Honoraria by Novartis, Pfizer, Incyte, Celgene, outside the submitted work. Fabio Efficace: personal fees from Bristol-Myers Squibb, Amgen, Orsenix, Incyte and Takeda; grants from Amgen, outside the submitted work. Mario Luppi: Advisory Boards: Novartis, Gilead Sci, Abbvie, Celgene, MSD, Sanofi, Daiichi-Sankyo; Travel Grant Gilead sci, outside the submitted work. Giuseppe A. Palumbo: Honoraria from Jannsen, Novartis, Celgene, Amgen, outside the submitted work. Marco Vignetti: personal fees from Jazz Healthcare Italy SRL, Amgen, Millennium Pharmaceuticals Inc., Celgene, Janssen, Novartis and Incyte, outside the submitted work.