Motta, Sarah E.
Fioretta, Emanuela S.
Dijkman, Petra E.
Lintas, Valentina
Behr, Luc
Hoerstrup, Simon P.
Emmert, Maximilian Y.
Article History
Received: 5 January 2018
Accepted: 5 March 2018
First Online: 20 March 2018
Compliance with Ethical Standards
:
: All the authors have no conflicts of interest to declare. Author Sarah E. Motta declares that she has no conflict of interest. Author Emanuela S. Fioretta declares that she has no conflict of interest. Author Petra E. Dijkman declares that she has no conflict of interest. Author Valentina Lintas declares that she has no conflict of interest. Author Luc Behr declares that he has no conflict of interest. Author Simon P. Hoerstrup declares that he has no conflict of interest. Author Maximilian Y. Emmert declares that he has no conflict of interest.
: All institutional and national guidelines for the care and use of laboratory animals were followed and approved by the appropriate institutional committees. All procedures performed in studies involving animals were in accordance with the ethical standards of the institution or practice at which the studies were conducted.
: This article does not contain any studies with human participants performed by any of the authors.
: Valve geometry is considered a key factor to achieve a favourable remodelling and long-term functionality in TEHVs thereby building the basis for a safe clinical translation. To date, none of the currently used transcatheter TEHV solutions feature the sinus of Valsalva in their stent geometry. In this study, we demonstrated the technical feasibility of combining a sinus-shape stent with in vitro grown ECM-based TEHVs fully compatible with transcatheter implantation procedures.