Guan, Chi
Yang, Yingxin
Tian, Dong
Jiang, Zhiqiang
Zhang, Huiying
Li, Yali
Yan, Jiaxiu
Zhang, Congman
Chen, Chun
Zhang, Junhua
Wang, Jing
Wang, Yu
Du, Hongwen
Zhou, Hongyu
Wang, Tao http://orcid.org/0000-0002-2620-5077
Article History
Accepted: 29 May 2022
First Online: 22 June 2022
Declarations
:
: The trials were supported by (DMPK) Department, Pharmaron, Beijing, China.
: Authors have no conflicts of interest to declare.
: All studies were approved by Pharmaron’s Institutional Animal Care and Use Committee (IACUC). All procedures and the care of the rats were in accordance with the National Guidelines for Experimental Animal Welfare (MOST, China, 2006) at the Center for Animal Experiments, which has full accreditation from the Association for Assessment and Accreditation of Laboratory Animal Care International. Maximum effort was exerted to minimize animal suffering and the number of animals necessary for the attainment of reliable data.
: Not applicable.
: Not applicable.
: Data supporting the findings are available from the corresponding author upon request.
: The proprietary software program GraphPad was used for the analysis reported here.
: C.G., D.T., Y.X.Y., and T.W. contributed to interpretation of the results as well as drafting and revising the manuscript, and agree to be accountable for all aspects of the work. J.H.Z., J.W., Y.W., and J.Y. contributed to data analysis. T.W., H.Y.Z., H.W.D., C.G., Y.X.Y., Z.Q.J., H.Y.Z., Y.L.L., J.X.Y., C.M.Z., and C.C. contributed to planning, design, and data collection of this analysis.