Kircik, Leon http://orcid.org/0000-0002-0831-2151
Zirwas, Matthew http://orcid.org/0000-0002-8380-8114
Kwatra, Shawn G. http://orcid.org/0000-0003-3736-1515
Lewitt, G. Michael
Glover, Holly
Chao, Tomas
Brown, Philip M.
Rubenstein, David S. http://orcid.org/0000-0003-0302-8722
Tallman, Anna M. http://orcid.org/0000-0001-9535-0414
Clinical trials referenced in this document:
Documents that mention this clinical trial
Rapid Improvements in Itch with Tapinarof Cream 1% Once Daily in Two Phase 3 Trials in Adults with Mild to Severe Plaque Psoriasis
https://doi.org/10.1007/s13555-023-01068-x
Tapinarof Cream 1% Once Daily for the Treatment of Plaque Psoriasis: Case Photography of Clinical Outcomes from Three Phase 3 Trials
https://doi.org/10.1007/s13555-023-01008-9
Documents that mention this clinical trial
Rapid Improvements in Itch with Tapinarof Cream 1% Once Daily in Two Phase 3 Trials in Adults with Mild to Severe Plaque Psoriasis
https://doi.org/10.1007/s13555-023-01068-x
Tapinarof Cream 1% Once Daily for the Treatment of Plaque Psoriasis: Case Photography of Clinical Outcomes from Three Phase 3 Trials
https://doi.org/10.1007/s13555-023-01008-9
Article History
Received: 7 September 2023
Accepted: 2 November 2023
First Online: 21 December 2023
Declarations
:
: Leon Kircik has served as a consultant, speaker, investigator, or advisory board member for Abbott Laboratories, AbbVie, Ablynx, Aclaris, Acambis, Allergan, Inc., Almirall, Amgen, Inc., Anacor Pharmaceuticals, AnaptysBio, Arcutis Biotherapeutics, Arena Pharmaceuticals, Assos Pharmaceuticals, Astellas Pharma US, Inc., Asubio Pharmaceuticals, Bausch Health, Berlex Laboratories (Bayer HealthCare Pharmaceuticals), Biogen Idec, BioLife, Biopelle, Bristol Myers Squibb, Boehringer Ingelheim, Breckenridge Pharma, Cassiopea SpA, Centocor, Inc., Cellceutix, Cipher Pharmaceuticals, Coherus BioSciences, Colbar LifeScience, Combinatrix, Connetics Corporation, Coria Laboratories, Dermavant Sciences, Inc., Dermira, Dermik Laboratories, Dow Pharmaceutical Sciences, Inc., Dr. Reddy’s Laboratories, DUSA Pharmaceuticals, Embil Pharmaceutical Co. Ltd., Eli Lilly, EOS, Exeltis, Ferndale Laboratories, Inc., Ferrer, Foamix Pharmaceuticals, Galderma, Genentech, Inc., GlaxoSmithKline, Glenmark Pharmaceuticals, Healthpoint, Ltd, Idera Pharmaceuticals, Incyte, Intendis, Innocutis, Innovail, ISDIN, Johnson & Johnson, Kyowa Kirin, Laboratory Skin Care Inc., LEO Pharma, L’Oréal, 3M, Maruho Co., Ltd., Medical International Technologies, Merck, Medicis Pharmaceutical Corp., Merz Pharma, NanoBio, Novartis AG, Noven Pharmaceuticals, Nucryst Pharmaceuticals Corp., Obagi, Onset Dermatologics, Ortho Neutrogena, Pediapharma, Pfizer, Promius Pharma, PuraCap, Pharmaderm, QLT, Inc., Quinnova Pharmaceuticals, Quatrix, Regeneron, Sanofi, Serono (Merck Serono International SA), SkinMedica, Inc., Stiefel Laboratories, Inc., Sun Pharma, Taro Pharmaceutical Industries, Toler Rx, Triax Pharmaceuticals, UCB Pharma, Valeant Pharmaceuticals Intl., Warner Chilcott, XenoPort, and ZAGE. Matthew Zirwas has served as an advisor, consultant, investigator, owner, or speaker for AbbVie, All Free Clear, Amgen, Inc., AnaptysBio, Arcutis Biotherapeutics, Aseptic MD, Biocon, Cara Therapeutics, Concert Pharmaceuticals, Dermavant Sciences, Inc., Edessa Biotech, Eli Lilly, EPI Health, Evelo Biosciences, Fitbit, Galderma, Genentech, Inc., Incyte, L’Oréal, LEO Pharma, Level Ex, LUUM, Novartis, Oculus Innovative Sciences, Peloton, Pfizer, Regeneron Pharmaceuticals, Sanofi, Sun Pharma, Trevi Therapeutics, UCB Pharma, and Vial. Shawn G. Kwatra has served as an investigator, advisory board member, or consultant for AbbVie, Aslan Pharmaceuticals, Arcutis Biotherapeutics, Castle Biosciences, Celldex Therapeutics, Galderma, Genzada Pharmaceuticals, Incyte, Johnson & Johnson, LEO Pharma, Novartis Pharmaceuticals Corporation, Pfizer, Regeneron Pharmaceuticals, and Sanofi. G. Michael Lewitt has served as a consultant, speaker, investigator, or advisory board member for and/or has received grants from AbbVie, Amgen, Inc., Bristol Myers Squibb, Dermavant Sciences, Inc., DermTech, Eli Lilly, Galderma, LEO Pharma, Janssen, Novan, Inc., Pfizer, Orthodermatologics, and UCB Pharma. Holly Glover has served as a consultant, speaker, investigator, or advisory board member of AbbVie, Almirall, Bristol Myers Squibb, Cassiopea SpA, Dermavant Sciences, Inc., Eli Lilly, Galderma, Incyte, ISDIN, LEO Pharma, Pfizer, and Sun Pharma. Tomas Chao has served as an advisor and speaker for Dermavant Sciences, Inc. Philip M. Brown, David S. Rubenstein, and Anna M. Tallman are employees of Dermavant Sciences, Inc., with stock options.
: The trials were conducted in accordance with Good Clinical Practice and the Declaration of Helsinki. Approval was obtained from the local ethics committee or institutional review board for each trial center. All patients provided written informed consent.