Sun, Rui
Bustamante, Mercedes
Gurusamy, Venkatesh Kumar
Lebwohl, Mark
Gottlieb, Alice B.
Mease, Philip J.
Deodhar, Atul
Bao, Weibin
Mendelson, Meryl
Porter, Brian
Chand, Deepa
Dong, Victor
Funding for this research was provided by:
Novartis
Article History
Received: 9 January 2024
Accepted: 14 February 2024
First Online: 7 March 2024
Declarations
:
: Mark Lebwohl is an employee of Mount Sinai and receives research funds from Abbvie, Amgen, Arcutis, Avotres, Boehringer Ingelheim, Cara therapeutics, Dermavant Sciences, Eli Lilly, Incyte, Inozyme, Janssen Research & Development, LLC, Ortho Dermatologics, Pfizer, Sanofi-Regeneron, and UCB, Inc., and is a consultant for Almirall, AltruBio Inc., Anaptys Bio, Apogee, Arcutis, Inc., AstraZeneca, Atomwise, Avotres Therapeutics, Brickell Biotech, Boehringer Ingelheim, Bristol Myers Squibb, Castle Biosciences, Celltrion, Corevitas, Dermavant Sciences, EPI, Evommune, Inc., Facilitation of International Dermatology Education, Forte biosciences, Foundation for Research and Education in Dermatology, Galderma, Genentech, Incyte, LEO Pharma, Meiji Seika Pharma, Mindera, Pfizer, Sanofi-Regeneron, Seanergy, Strata, Takeda, Trevi, and Verrica. Alice B Gottlieb has received research/educational grants from Anaptyps Bio, Highlights Therapeutics, Moonlake Immunotherapeutics AG, Janssen, Novartis, Bristol Myers Squibb, and UCB Pharma, (all paid to Mount Sinai School of Medicine); has received honoraria as an advisory board member and consultant for Amgen, Anaptyps Bio, Avotres Therapeutics, Boehringer Ingelheim, Bristol Myers Squibb, Dice Therapeutics, Eli Lilly, Highlights Therapeutics, Janssen, Novartis, Sanofi, UCB, and Xbiotech. Philip J Mease has received grant/research support from AbbVie, Amgen, Bristol Myers Squibb, Celgene, Crescendo Bioscience, Genentech, Janssen, Eli Lilly, Merck, Novartis, Pfizer and UCB; is a consultant for: AbbVie, Amgen, BMS, Celgene, Crescendo Bioscience, Genentech, Janssen, Eli Lilly, Merck, Novartis, Pfizer, and UCB; Speakers bureau: AbbVie, Amgen, Bristol Myers Squibb, Celgene, Crescendo Bioscience, Genentech, Janssen, Eli Lilly, Merck, Novartis, Pfizer, and UCB. Atul Deodhar has received honoraria for consulting or speaking for, or has received research grants from AbbVie, Bristol Myers Squibb, Eli Lilly, Janssen, Novartis, Pfizer, and UCB. Venkatesh Kumar Gurusamy is employee of Novartis. Rui Sun, Mercedes Bustamante, Weibin Bao, Meryl Mendelson, Brian Porter, Deepa Chand, and Victor Dong are employees and own shares of Novartis.
: All AEs were assessed in accordance with Good Pharmacovigilance Practice Module VII and International Council for Harmonization (ICH) Guideline E2C. All CTs were conducted in compliance with the Declaration of Helsinki, ICH Guidelines for Good Clinical Practice, and local country regulations. The protocols for the clinical trials were reviewed and approved by ethical review committees and authorities for each clinical site; all patients provided written informed consent.