Uchida, Kazutaka
Ueda, Shinichiro
Sakakibara, Fumihiro
Kinjo, Norito
Nezu, Mari
Arai, Hideki
Morimoto, Takeshi http://orcid.org/0000-0002-6844-739X
Funding for this research was provided by:
Bristol-Myers Squibb
Japan Society for the Promotion of Science (JP21H03176)
Article History
Accepted: 4 October 2022
First Online: 16 November 2022
Declarations
:
: This study was supported in part by Bristol-Myers Squibb and JSPS KAKENHI (JP21H03176). The funders did not participate in any part of the study from conception to article preparation.
: Kazutaka Uchida reports lecturer’s fees from Daiichi Sankyo. Shinichiro Ueda reports receiving research grants from Bristol-Myers Squibb, Chugai, Kowa, MSD, Pfizer, and Takeda; lecturer’s fee from Boehringer Ingelheim, MSD, and Taiho; and manuscript fees from Kowa. He has also served on an advisory board for Otsuka. Takeshi Morimoto reports lecturer’s fees from AstraZeneca, Bristol-Myers Squibb, Daiichi Sankyo, Japan Lifeline, Kowa, Toray, and Tsumura; manuscript fees from Bristol-Myers Squibb and Kowa; and advisory board fees from Novartis and Teijin. Norito Kinjo, Fumihiro Sakakibara, Mari Nezu, and Hideki Arai have no disclosures to report.
: The data supporting this study’s findings are available from the corresponding author upon reasonable request.
: The Institutional Review Boards of all 71 participating sites approved the study protocol in accordance with the Ethical Guidelines for Medical and Health Research Involving Human Subjects in Japan Declaration of Helsinki.
: The Institutional Review Boards approved the opt-out method in place of written informed consent.
: TM and SU: Study conception and design; data acquisition and management. KU, TM, FS and NK: Statistical analyses. All authors: Interpretation of the data. KU and TM: Drafting of the manuscript. FS, NK, MN, HA, and SU: Critical revision of the manuscript. All authors: Final approval of the manuscript.
: Written informed consent from each participant was substituted by opt-out method under the approval from the institutional review boards.
: Consent for publication from study participants was not obtained because the opt-out method was used.
: The code supporting the study findings are available from the corresponding author upon reasonable request.