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Documents that mention this clinical trial
Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: A Randomized Phase II Study of the First Triple-Combination Drug
Accepted: 12 October 2021
First Online: 21 October 2021
: The study was funded by Ortho Dermatologics. Medical writing support for this article was also funded by Ortho Dermatologics.
: Linda Stein Gold has served as an investigator/consultant or speaker for Ortho Dermatologics, LEO Pharma, Dermavant, Incyte, Novartis, AbbVie, Pfizer, Sun Pharma, UCB, Arcutis, and Lilly. Hilary Baldwin has served as an advisor or investigator and on speakers’ bureaus for Almirall, Cassiopea, Foamix, Galderma, Ortho Dermatologics, Sol Gel, and Sun Pharma. Leon H. Kircik has acted as an investigator, advisor, speaker, and consultant for Ortho Dermatologics. Jonathan S. Weiss is a consultant, speaker, advisor, and/or researcher for AbbVie, Ortho Dermatologics, Janssen Biotech, Dermira, Almirall, Brickell Biotech, DermTech, and Scynexis. David M. Pariser has served as a consultant to Atacama Therapeutics, Bickel Biotechnology, Biofrontera AG, Celgene, Dermira, LEO Pharma, Regeneron, Sanofi, TDM SurgiTech, TheraVida, and Ortho Dermatologics; an investigator for Abbott Laboratories, Almirall, Amgen, AOBiome, Asana Biosciences, Bickel Biotechnology, Celgene, Dermavant, Dermira, Eli Lilly, LEO Pharma, Menlo Therapeutics, Merck & Co., Novartis, Novo Nordisk A/S, Ortho Dermatologics, Pfizer, Regeneron, and Stiefel; on the advisory board for Pfizer; and on the data monitoring board for BMS. Valerie Callender has served as an investigator, consultant, or speaker for AbbVie, Galderma, L’Oréal, Ortho Dermatologics, and Vyne. Edward Lain has nothing to disclose. Michael Gold has acted as an investigator, advisor, speaker, and consultant for Ortho Dermatologics. Kenneth Beer has received funding from Allergan, Galderma, Evolus, and Revance. Zoe Draelos received research funding from Ortho Dermatologics. Neil Sadick has served on advisory boards, as a consultant, investigator, speaker, and/or other and has received honoraria and/or grants/research funding from Almirall, Actavis, Allergan, Anacor Pharmaceuticals, Auxilium Pharmaceuticals, Bausch Health, Bayer, Biorasi, BTG, Carma Laboratories, Cassiopea, Celgene Corporation, Cutera, Cynosure, DUSA Pharmaceuticals, Eclipse Medical, Eli Lilly and Company, Endo International, EndyMed Medical, Ferndale Laboratories, Galderma, Gerson Lehrman Group, Hydropeptide, Merz Aesthetics, Neostrata, Novartis, Nutraceutical Wellness, Palomar Medical Technologies, Prescriber’s Choice, Regeneron, Roche Laboratories, Samumed, Solta Medical, Storz Medical AG, Suneva Medical, Vanda Pharmaceuticals, and Venus Concept. Radhakrishnan Pillai and Varsha Bhatt are employees of Bausch Health US, LLC and may hold stock and/or stock options in its parent company. Emil A. Tanghetti has served as a speaker for Novartis, Ortho Dermatologics, Sun Pharma, Lilly, Galderma, AbbVie, and Dermira; served as a consultant in clinical studies for Hologic, Ortho Dermatologics, and Galderma; and is a stockholder for Accure.
: This study was carried out in accordance with principles of Good Clinical Practice and the Declaration of Helsinki. At all investigational sites, the study protocol was approved by the relevant independent ethics committees or institutional review boards. All participants or their legal guardians provided written informed consent.
: All participants or their legal guardians provided written informed consent before entering the clinical trial from which the data were derived.
: Additional informed consent was obtained from all individual participants for whom identifying information/photographs are included in this article.
: Available upon request.
: Not applicable.
: All authors made substantial contributions to the conception or design of the work; drafted the work/revised it critically; approved the version to be published; and agree to be accountable for all aspects of this work.