Jones, Matthew D. http://orcid.org/0000-0002-2617-4098
Franklin, Bryony Dean http://orcid.org/0000-0002-2892-1245
Raynor, D. K. http://orcid.org/0000-0003-0306-5275
Thom, Howard http://orcid.org/0000-0001-8576-5552
Watson, Margaret C. http://orcid.org/0000-0002-8198-9273
Kandiyali, Rebecca http://orcid.org/0000-0001-8566-9536
Funding for this research was provided by:
National Institute for Health Research (TRF-2017-10-006)
Article History
Accepted: 12 July 2021
First Online: 17 August 2021
Declarations
:
: Matthew Jones is funded by a National Institute for Health Research (NIHR), Transitional Research Fellowship for this research project (grant number TRF-2017-10-006). Howard Thom was supported by the NIHR Biomedical Research Centre at University Hospitals Bristol and Weston NHS Foundation Trust and the University of Bristol. Margaret Watson was funded by a Health Foundation Improvement Science Fellowship. Bryony Dean Franklin is supported by the NIHR Imperial Patient Safety Translational Research Centre and the NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance at Imperial College in partnership with Public Health England (PHE).
: MDJ has received an honorarium from B. Braun Medical Ltd for speaking at an educational symposium on injectable medicines safety. DKR is academic advisor to Luto Research which develops, refines and tests health information materials. BDF has received honoraria from Pfizer for organising and chairing two educational symposia on medication safety, and recently supervised a Ph.D. student who was part funded by Cerner, an electronic health record systems vendor. HT has received consulting fees from Pfizer, Roche, Janssen, Novartis, and Bayer. For the remaining authors, none were declared.
: The model and supporting data created during this research are openly available from the University of Bath Research Data Archive at ExternalRef removed.
: The model created during this research is openly available from the University of Bath Research Data Archive at ExternalRef removed.
: The clinical study that provided many of the input data was performed in line with the principles of the Declaration of Helsinki. Approval was granted by the University of Bath Research Ethics Approval Committee for Health (EP17/18-192) and the United Kingdom's Health Research Authority (IRAS 242505). Participants gave written, informed consent before taking part. This included consent to the publication of anonymised research data.
: All authors contributed to the study conception and design. Primary data collection and identification of data inputs were performed by Matthew Jones. Model development and analysis were performed by Matthew Jones, Howard Thom and Rebecca Kandiyali. The first draft of the manuscript was written by Matthew Jones and all authors contributed to and approved the final manuscript.