Dubinsky, Samuel
Malik, Paul
Hajducek, Dagmar M.
Edginton, Andrea http://orcid.org/0000-0002-9014-1653
Article History
Accepted: 6 March 2022
First Online: 5 May 2022
Declarations
:
: No sources of funding were received for the preparation of this article.
: The authors have no conflicts of interest that are directly relevant to the content of this article.
: Not applicable.
: Not applicable.
: Not applicable.
: Not applicable.
: Not applicable.
: SD, PM, and AE conceptualized the idea and topic of this article. SD and PM contributed to a healthy adult PBPK model construction of the investigative drugs analyzed within this article. SD conducted the CKD-PBPK simulations and analyzed the results. DH was instrumental in the development and finalization of the OAT parameterization function used throughout the CKD-PBPK simulations. Contributions from PM were final as of 11 June, 2021. Preparation of the final manuscript was conducted by SD. The final version of manuscript was reviewed by all authors.