King, Clare E. http://orcid.org/0000-0002-6336-5459
Pratt, Nicole L. http://orcid.org/0000-0001-8730-8910
Craig, Nichole
Thai, Loc
Wilson, Margaret http://orcid.org/0000-0003-1485-8852
Nandapalan, Neillan http://orcid.org/0000-0002-3182-6804
Kalisch Ellet, Lisa http://orcid.org/0000-0001-5063-6128
Behm, Eirene C. http://orcid.org/0000-0002-6506-1846
Funding for this research was provided by:
National Health and Medical Research Council (GNT 1040938, GNT 1157506, APP1101788)
Article History
First Online: 23 June 2020
Compliance with Ethical Standards
:
: All authors contributed to study conception and design. Data collection and analysis were performed by LT and NC, with the statistical code provided by NLP. Interpretation of the results was performed by CEK, MW, NN, ECB, NLP and LKE. The first draft of the manuscript was written by CEK and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.
: The list of PSSA signals for furosemide initiation is provided in Appendix A in the Electronic Supplementary Materials. No additional data available. The data that support the findings of this study are available from the Australian Government Department of Health but restrictions apply to the availability of these data, and so are not publicly available.
: NP was funded by a National Health and Medical Research Centre (NHMRC) Grant, Centre of Research Excellence in post-marketing surveillance of medicines and medical devices GNT 1040938 and NHMRC Project Grant GNT 1157506. LKE was supported by an NHMRC-ARC Dementia Research Development Fellowship (Grant identification number APP1101788).
: All authors have no conflicts of interest that are directly relevant to the content of the manuscript.
: The PBS data fields used in the study were medicine item code, supply date of medicine and patient identification (ID) key. As the patient ID key was a unique data key rather than a number that can be used to re-identify individuals, the research was considered negligible risk under the National Statement on Ethical Conduct in Human Research. The project was discussed with the Department of Health Human Research Ethics Committee, but formal ethics approval was not required.
: The results of the study have not been published previously.