Simons, Martijn J. H. G. http://orcid.org/0000-0001-5248-1676
Retèl, Valesca P. http://orcid.org/0000-0002-5624-3234
Ramaekers, Bram L. T. http://orcid.org/0000-0001-5785-9228
Butter, Rogier http://orcid.org/0000-0002-4277-6814
Mankor, Joanne M. http://orcid.org/0000-0003-3653-9043
Paats, Marthe S.
Aerts, Joachim G. J. V. http://orcid.org/0000-0001-6662-2951
Mfumbilwa, Zakile A. http://orcid.org/0000-0002-9705-7227
Roepman, Paul http://orcid.org/0000-0003-1566-0258
Coupé, Veerle M. H. http://orcid.org/0000-0002-9553-9791
Uyl-de Groot, Carin A. http://orcid.org/0000-0001-6492-5203
van Harten, Wim H. http://orcid.org/0000-0001-9580-0489
Joore, Manuela A. http://orcid.org/0000-0002-5649-6768
Funding for this research was provided by:
ZonMw (846001002)
KWF Kankerbestrijding
Achmea
Article History
Accepted: 25 July 2021
First Online: 18 August 2021
Declarations
:
: This work was supported by the Netherlands Organisation for Health Research and Development (ZonMw) (grant number 846001002), the Dutch Cancer Society (KWF), and the Dutch healthcare insurance company Zilveren kruis Achmea. The funding sources had no involvement in the conduct of this research. The open access fee was paid by the Maastricht University Medical Centre and the Maastricht University.
: Bram Ramaekers, Rogier Butter, Joanne Mankor, Marthe Paats, Paul Roepman, Carin Uyl-de Groot, Wim van Harten, and Manuela Joore have no conflicts of interest that are directly relevant to the content of this article. Martijn Simons, Zakile Mfumbilwa, and Veerle Coupé have received grants from governmental funding of medical research by ZonMw. Valesca Retèl has received grants from Agendia B.V. and Intuitive Surgical outside the submitted work. Joachim Aerts has received personal fees and non-financial support from Biocad outside the submitted work; holds stock options with Amphera; and has a patent in allogenic tumour cell lysate licensed to Amphera, combination immunotherapy in cancer pending, and biomarker for immunotherapy pending.
: All data generated or analysed during this study are included in this published article and its supplementary information files. The model created during the current study is available in the Zenodo repository [ExternalRef removed] [CitationRef removed].
: Not applicable.
: Not applicable.
: Not applicable.
: The used model was created in Microsoft Excel.
: MS: Conceptualisation and design, data acquisition, methodology, formal analysis and interpretation of the data, investigation, validation, writing original draft, writing review and editing, and critical revision of the article for important intellectual content. VR and MJ: Conceptualisation and design, methodology, formal analysis and interpretation of the data, writing original draft, supervision, writing review and editing, and critical revision of the article for important intellectual content. BR: Conceptualisation and design, methodology, formal analysis and interpretation of the data, writing original draft, writing review and editing, and critical revision of the article for important intellectual content. RB, JM, MP, JA, PR: Validation and interpretation of the data, writing review and editing, and critical revision of the article for important intellectual content. ZM and VC: Methodology, validation and interpretation of the data, writing review and editing, and critical revision of the article for important intellectual content. CUG: Interpretation of the data, writing review and editing, and critical revision of the article for important intellectual content. WH: Interpretation of the data, writing review and editing, supervision, and critical revision of the article for important intellectual content.