Berumen, J. http://orcid.org/0000-0001-6707-3317
Orozco, L. http://orcid.org/0000-0002-5801-9180
Gallardo-Rincón, H. http://orcid.org/0000-0002-0811-4606
Juárez-Torres, E.
Barrera, E.
Cruz-López, M. http://orcid.org/0000-0001-9985-6172
Benuto, R. E.
Ramos-Martinez, E. http://orcid.org/0000-0002-4361-821X
Marin-Madina, M.
Alvarado-Silva, A.
Valladares-Salgado, A.
Peralta-Romero, J. J. http://orcid.org/0000-0001-5426-5555
García-Ortiz, H. http://orcid.org/0000-0002-0453-980X
Martinez-Juarez, L. A. http://orcid.org/0000-0001-7550-7867
Montoya, A.
Alvarez-Hernández, D. A. http://orcid.org/0000-0003-2340-6639
Alegre-Diaz, J. http://orcid.org/0000-0001-9390-3871
Kuri-Morales, P. http://orcid.org/0000-0002-0704-9507
Tapia-Conyer, R. http://orcid.org/0000-0001-9425-7322
Funding for this research was provided by:
Carlos Slim Foundation
Laboratorio Huella Génica
Faculty of Medicine of the National Autonomous University of Mexico
Article History
Received: 24 February 2023
Accepted: 5 August 2023
First Online: 25 August 2023
Declarations
:
: All authors have nothing to disclose.
: The protocol for the main study was approved by the local ethics committee of each study site and the Federal Commission for the Protection Against Health Risks (COFEPRIS) (CAS/OR/CMN/113300410D0027-0577/2012). The clinical replica study was approved by the Ethics and Research Committees of the Comisión Nacional de Investigación Científica of the Instituto Mexicano del Seguro Social (IMSS R-2014-785-005), while the cross-sectional study was approved by the Ethics and Research Committees of the Hospital General de Puebla “Ignacio Romero Vargas” (68/ENS/INV/REV/2017). All protocols complied with the Declaration of Helsinki and local ethical guidelines for clinical studies in Mexico.
: Written informed consent was obtained from all participants.