Shah, Riyaz http://orcid.org/0000-0003-3374-077X
Girard, Nicolas
Nagar, Saurabh P.
Griesinger, Frank
Roeper, Julia
Davis, Keith L.
Karimi, Parisa
Sawyer, William
Yu, Ning
Taylor, Aliki
Feliciano, Josephine
Funding for this research was provided by:
AstraZeneca, Cambridge, UK
Article History
Accepted: 14 May 2021
First Online: 17 September 2021
Declarations
:
: This work was supported by AstraZeneca Cambridge, UK, the manufacturer of osimertinib.
: Riyaz Shah has received fees for honoraria and has served on advisory councils/committees for AstraZeneca and Roche. Nicolas Girard has served on advisory councils/committees for AstraZeneca, Boehringer Ingelheim, Pfizer, and Roche and has received consultancy fees and other fees from AstraZeneca, Boehringer Ingelheim, Pfizer, and Roche. Saurabh P. Nagar and Keith L. Davis are employees of RTI Health Solutions, which received contract research funding from AstraZeneca for the conduct of this study. Frank Griesinger has served on advisory councils/committees for AstraZeneca, Boehringer Ingelheim, Pfizer, and Roche and has received fees for honoraria and research funding from AstraZeneca, Boehringer Ingelheim, Pfizer, and Roche. Julia Roeper has no conflicts of interest that are directly relevant to the content of this article. Parisa Karimi, Ning Yu, and Aliki Taylor are employees of AstraZeneca and own stocks or shares in AstraZeneca. William Sawyer is a contract employee of AstraZeneca. Josephine Feliciano has received research funding from AstraZeneca, Bristol Myers Squibb, and Pfizer and has received consultancy fees from AstraZeneca, Bristol Myers Squibb, Eli Lilly and Company, Genentech, and Takeda.
: Data underlying the findings described in this manuscript may be obtained in accordance with AstraZeneca’s data-sharing policy described at: ExternalRef removed.
: This study was conducted in accordance with local standards in the USA, UK, France, and Germany. The study was performed in accordance with the ethical principles of the Declaration of Helsinki, the International Conference on Harmonization, and good clinical practice.
: Not applicable.
: Conception and design: Saurabh P. Nagar, Keith L. Davis, William Sawyer, and Aliki Taylor. Data analysis and interpretation, manuscript writing, and final approval of manuscript: all authors. All authors agree to be accountable for all aspects of the work.
: The authors thank all the patients and their families. Thanks also to Bharat Thakrar for his scientific input into the study development. Medical writing support for the development of this manuscript, under the direction of the authors, was provided by Louise Prince, PhD, of Ashfield MedComms, an Ashfield Health company, and funded by AstraZeneca Cambridge, UK, in accordance with Good Publications Practice guidelines (ExternalRef removed).