Uchiyama, Makoto
Ito, Kaoru http://orcid.org/0000-0002-3348-1969
Okumura, Yasuyuki
Yi, Jingbo
Crawford, Bruce
Abe, Machiko
Funding for this research was provided by:
MSD K.K.
Article History
Accepted: 2 September 2021
First Online: 7 February 2022
Declarations
:
: This study was supported by MSD K.K. (Tokyo, Japan) through a research contract with Market Access, MSD K.K., Tokyo, Japan. The funder participated in study design, interpretation of data, and writing, review, and approving the publication.
: M.U. has received research support from Astellas Pharma, Eisai, Meiji Seika Pharma, MSD K.K., Pfizer Japan, Shionogi & Co, Taisho Pharmaceutical, Kao Corporation, and Takeda Pharmaceutical; had a consulting role for Idorsia Pharmaceuticals Japan, Kao Corporation, Taisho Pharmaceutical, and Takeda Pharmaceutical; and has received honoraria for giving lectures and/or contributing text from Astellas Pharma, Eisai, Otsuka Pharmaceutical, Meiji Seika Pharma, MSD K.K., and Takeda Pharmaceutical. K.I. was an employee of the sponsoring company (MSD K.K., Tokyo, Japan) at the time of study conduct. M.A. is an employee of the sponsoring company (MSD K.K., Tokyo, Japan). MSD K.K., Tokyo, Japan manufactures a product for the treatment of insomnia. B.C. and J.Y. are employees of Syneos Health, a healthcare contract research organization. Y.O. has received personal fees from MSD K.K., Otsuka Pharmaceutical, Cando, Japan Medical Data Center, and Japan Medical Research Institute.
: The study was approved by an independent ethics committee, and the data were fully anonymized by Japan Medical Data Center Inc. to ensure data privacy.
: Not applicable.
: Not applicable.
: Data sharing not applicable—no new data generated, or the article describes entirely theoretical research.
: Not applicable.
: KI, YO, and BC designed the study protocol and methods. BC and JY conducted the statistical analysis and co-wrote the manuscript. MU and YO interpreted the results and served as advisors to guide writing of the manuscript. KI and MA supervised the research.