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ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy

Crossref DOI link: https://doi.org/10.1038/nature24016

Published Online: 2017-09-20

Published Print: 2017-09

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

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Shi, Yang

Yamada, Kaoru

Liddelow, Shane Antony

Smith, Scott T.

Zhao, Lingzhi

Luo, Wenjie

Tsai, Richard M.

Spina, Salvatore

Grinberg, Lea T.

Rojas, Julio C.

Gallardo, Gilbert

Wang, Kairuo

Roh, Joseph

Robinson, Grace

Finn, Mary Beth

Jiang, Hong

Sullivan, Patrick M.

Baufeld, Caroline

Wood, Michael W.

Sutphen, Courtney

McCue, Lena

Xiong, Chengjie

Del-Aguila, Jorge L.

Morris, John C.

Cruchaga, Carlos

Fagan, Anne M.

Miller, Bruce L.

Boxer, Adam L.

Seeley, William W.

Butovsky, Oleg

Barres, Ben A.

Paul, Steven M.

Holtzman, David M.
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Article History

Received: 25 November 2016

Accepted: 17 August 2017

First Online: 20 September 2017

Competing interests

: D.M.H. co-founded and is on the scientific advisory board of C<sub>2</sub>N Diagnostics. He consults for Genentech, AbbVie, Eli Lilly, Proclara, GlaxoSmithKline, and Denali. Washington University receives research grants to the laboratory of D.M.H. from C2N Diagnostics, Eli Lilly, AbbVie, and Denali.