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Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo

Crossref DOI link: https://doi.org/10.1038/nbt.3081

Published Online: 2014-10-30

Published Print: 2015-01

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Zuris, John A

Thompson, David B

Shu, Yilai

Guilinger, John P

Bessen, Jeffrey L

Hu, Johnny H

Maeder, Morgan L

Joung, J Keith

Chen, Zheng-Yi

Liu, David R
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Article History

Received: 22 July 2014

Accepted: 23 October 2014

First Online: 30 October 2014

Competing interests

: The co-authors have filed a provisional patent application related to this work. J.K.J. and D.R.L. are cofounders of consultants for Editas Medicine, a company that applies genome-editing technologies. J.K.J. is a consultant for Horizon Discovery. J.K.J. has financial interests in Editas Medicine and Transposagen Biopharmaceuticals. J.K.J.'s interests were reviewed and are managed by Massachusetts General Hospital and Partners HealthCare in accordance with their conflict of interest policies. M.L.M. is currently an employee of Editas Medicine.