Article History
First Online: 6 May 2016
Competing interests
: J.K.J. is a consultant for Horizon Discovery. J.K.J. has financial interests in Editas Medicine, Hera Testing Laboratories, Poseida Therapeutics, and Transposagen Biopharmaceuticals. J.K.J.'s interests were reviewed and are managed by Massachusetts General Hospital and Partners HealthCare in accordance with their conflict of interest policies. S.Q.T., J.K.J. and M.J.A. are co-founders of Beacon Genomics, a company that is commercializing methods for determining nuclease specificity. S.Q.T. and J.K.J. have filed a patent application for the GUIDE-seq method.