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Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells

Crossref DOI link: https://doi.org/10.1038/nmeth.4038

Published Online: 2016-10-31

Published Print: 2016-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Hess, Gaelen T

Frésard, Laure

Han, Kyuho

Lee, Cameron H

Li, Amy

Cimprich, Karlene A

Montgomery, Stephen B

Bassik, Michael C
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Text and Data Mining valid from 2016-10-31
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Article History

Received: 3 June 2016

Accepted: 27 September 2016

First Online: 31 October 2016

Competing interests

: Stanford University has filed a patent application based on the findings in this article. US provisional patent application no. 62/376,681.